Moisture & Dry Skin – relevant products and ingredient information

Betamethasone Valerate / Dipropionate is a potent topical corticosteroid on the WHO Model List of Essential Medicines. It suppresses cutaneous inflammatory edema, erythema, and pruritus in eczema, psoriasis, and severe contact dermatitis. Often formulated in combination with Fusidic Acid, Gentamicin, or Miconazole to treat secondarily infected dermatoses.

Clobetasol Propionate (0.05% w/w) is an ultra-high potency (Class I) topical synthetic corticosteroid on the WHO Model List of Essential Medicines. It binds to intracellular glucocorticoid receptors, down-regulating inflammatory cytokines (IL-1, IL-2, TNF-alpha) and inducing lipocortins to block phospholipase A2 and arachidonic acid cascade products. Indicated for short-term management of moderate-to-severe plaque psoriasis, recalcitrant dermatoses, lichen planus, and severe discoid lupus erythematosus.

Mometasone Furoate (0.1% w/w cream/ointment) is a high-potency (Class II) synthetic topical corticosteroid on the WHO Model List of Essential Medicines. It features a high therapeutic index, providing robust anti-inflammatory and anti-pruritic activity with significantly lower systemic absorption and cutaneous atrophogenic potential than older fluorinated steroids. Indicated for relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, including atopic dermatitis and psoriasis.

Betamethasone Valerate / Dipropionate is a potent topical corticosteroid on the WHO Model List of Essential Medicines. It suppresses cutaneous inflammatory edema, erythema, and pruritus in eczema, psoriasis, and severe contact dermatitis. Often formulated in combination with Fusidic Acid, Gentamicin, or Miconazole to treat secondarily infected dermatoses.

Vitamin E Soft Gel Capsules (200mg, 400mg, 600mg) is an oral fat-soluble antioxidant (d-alpha-tocopheryl acetate) on the WHO Model List framework. It integrates into phospholipid cell membranes, where it traps peroxyl free radicals and halts the propagation of lipid peroxidation chain reactions, protecting polyunsaturated fatty acids in membranes, red blood cells, and vascular endothelial cells from oxidative injury. Indicated for vitamin E deficiency, supportive management of non-alcoholic fatty liver disease (NASH), peripheral neuropathy in abetalipoproteinemia, and adjuvant skin/hair health.

Glycerin 98% is an evidence-based dermatological formulation. It acts by delivering targeted active therapeutic ingredients to cutaneous lesions to relieve skin pathology, restore barrier integrity, and manage dermatoses.

Calamine lotion (Zinc Oxide and Ferric Oxide with Aloe Vera and Light Liquid Paraffin) is a classic topical soothing astringent and antipruritic on the WHO Model List of Essential Medicines. It evaporates to cool the skin, while zinc oxide provides mild antiseptic and protective barrier coverage. Indicated for symptomatic relief of itching, insect bites, sunburn, chickenpox rash, poison ivy, and prickly heat.

Vitamin E Soft Gel Capsules (200mg, 400mg, 600mg) is an oral fat-soluble antioxidant (d-alpha-tocopheryl acetate) on the WHO Model List framework. It integrates into phospholipid cell membranes, where it traps peroxyl free radicals and halts the propagation of lipid peroxidation chain reactions, protecting polyunsaturated fatty acids in membranes, red blood cells, and vascular endothelial cells from oxidative injury. Indicated for vitamin E deficiency, supportive management of non-alcoholic fatty liver disease (NASH), peripheral neuropathy in abetalipoproteinemia, and adjuvant skin/hair health.

Halobetasol Propionate (0.05% w/w) is an ultra-high potency (Class I) fluorinated topical corticosteroid. It produces intense vasoconstriction, suppression of immune cell migration, and potent anti-inflammatory action in severe hyperkeratotic and inflammatory skin conditions. Indicated for plaque psoriasis and severe steroid-responsive dermatoses.

Hydrocortisone Acetate (1% w/w) is a low-potency (Class VII) topical corticosteroid on the WHO Model List of Essential Medicines. It represents the safest topical steroid for sensitive skin areas (face, intertriginous skin folds, groin) and pediatric patients, providing anti-inflammatory, anti-pruritic, and mild vasoconstrictive actions with minimal risk of skin thinning or systemic absorption. Indicated for mild eczema, facial dermatitis, intertrigo, insect bites, and anogenital pruritus.

Urea (10% w/w) and Lactic Acid (10% w/w) intensive footcare cream is an osmotic keratolytic and humectant formulation. Urea dissolves intercellular matrix proteins and attracts moisture into the stratum corneum, while lactic acid gently exfoliates thickened, calloused epidermis. Indicated for dry, rough, cracked heels, xerosis, calluses, and ichthyotic skin conditions.

Cod liver oil 300MG + Evening primrose oil 300MG + Omega-3 fatty acid 90MG + Vitamin E 10MG Soft Gelatin Capsules is an evidence-based cardiovascular and hemodynamic pharmaceutical formulation. It acts by modulating vascular smooth muscle tone, autonomic receptors, or fluid-electrolyte balance to manage cardiovascular disease.

Vitamin B-Complex Formulations (Tablets, Capsules with Zinc, Syrup, and Injection) is a balanced formulation of essential B-group vitamins (B1 Thiamine, B2 Riboflavin, B3 Niacinamide, B5 Calcium Pantothenate, B6 Pyridoxine, B9 Folic Acid, B12 Cobalamin) on the WHO Model List of Essential Medicines. B-vitamins act as critical water-soluble coenzymes in cellular Krebs cycle energy production, carbohydrate and lipid metabolism, erythropoiesis, and myelin integrity. Indicated for prevention and treatment of generalized B-complex deficiencies, aphthous stomatitis/glossitis/angular cheilitis, convalescence, chronic debilitating illness, and nutritional maintenance during prolonged antibiotic therapy.

Lactic Acid 1.2% w/v Intimate Hygiene Wash is a dermatologically tested, soap-free topical wash enriched with natural lactic acid, tea tree oil, and sea buckthorn oil. It is scientifically formulated to preserve and maintain the optimal physiological acidic microenvironment (pH 3.5 to 4.5) of the female external vulvar area, supporting beneficial Lactobacillus flora and preventing the overgrowth of pathogenic bacteria and fungi responsible for bacterial vaginosis and candidiasis. Indicated for daily feminine external hygiene, during menstruation, post-partum recovery, and post-intimacy cleansing.

Aloe Vera 10% and Vitamin E 1% Moisturising Cream is an evidence-based dermatological formulation. It acts by delivering targeted active therapeutic ingredients to cutaneous lesions to relieve skin pathology, restore barrier integrity, and manage dermatoses.

Evening Primrose Oil Soft Gel Capsules (500mg, 1000mg) is an oral source of essential omega-6 fatty acids, specifically gamma-linolenic acid (GLA 9-10%) on the PMBI Formulary. GLA is metabolized into anti-inflammatory dihomo-gamma-linolenic acid (DGLA) and prostaglandin E1 (PGE1), suppressing pro-inflammatory cytokines and reducing breast tissue hyperresponsiveness to cyclic hormone fluctuations. Indicated for cyclical mastalgia (breast pain), premenstrual syndrome (PMS), and atopic eczema.

Calamine lotion (Zinc Oxide and Ferric Oxide with Aloe Vera and Light Liquid Paraffin) is a classic topical soothing astringent and antipruritic on the WHO Model List of Essential Medicines. It evaporates to cool the skin, while zinc oxide provides mild antiseptic and protective barrier coverage. Indicated for symptomatic relief of itching, insect bites, sunburn, chickenpox rash, poison ivy, and prickly heat.

Apremilast is an oral small-molecule phosphodiesterase 4 (PDE4) inhibitor on the WHO Model List of Essential Medicines. By inhibiting PDE4, it elevates intracellular cyclic adenosine monophosphate (cAMP), down-regulating pro-inflammatory cytokine expression (TNF-alpha, IL-17, IL-23) while up-regulating anti-inflammatory IL-10. Indicated for moderate-to-severe plaque psoriasis in adults who are candidates for phototherapy or systemic therapy, and active psoriatic arthritis.

Evening Primrose Oil Soft Gel Capsules (500mg, 1000mg) is an oral source of essential omega-6 fatty acids, specifically gamma-linolenic acid (GLA 9-10%) on the PMBI Formulary. GLA is metabolized into anti-inflammatory dihomo-gamma-linolenic acid (DGLA) and prostaglandin E1 (PGE1), suppressing pro-inflammatory cytokines and reducing breast tissue hyperresponsiveness to cyclic hormone fluctuations. Indicated for cyclical mastalgia (breast pain), premenstrual syndrome (PMS), and atopic eczema.

Apremilast is an oral small-molecule phosphodiesterase 4 (PDE4) inhibitor on the WHO Model List of Essential Medicines. By inhibiting PDE4, it elevates intracellular cyclic adenosine monophosphate (cAMP), down-regulating pro-inflammatory cytokine expression (TNF-alpha, IL-17, IL-23) while up-regulating anti-inflammatory IL-10. Indicated for moderate-to-severe plaque psoriasis in adults who are candidates for phototherapy or systemic therapy, and active psoriatic arthritis.

Tacrolimus (0.03%, 0.1% ointment) is a topical calcineurin inhibitor (TCI) and non-steroidal immunosuppressant on the WHO Model List of Essential Medicines. It binds to intracellular immunophilin FKBP-12, forming a complex that inhibits calcineurin phosphatase, preventing dephosphorylation of NF-AT and blocking transcription of pro-inflammatory cytokines (IL-2, IL-3, IL-4, IFN-gamma) in T-lymphocytes. Unlike steroids, it does not cause skin atrophy, telangiectasia, or collagen breakdown. Indicated for moderate-to-severe atopic dermatitis (eczema) in patients not adequately responsive to or intolerant of conventional topical therapies, especially on the face, neck, and flexures.

Apremilast is an oral small-molecule phosphodiesterase 4 (PDE4) inhibitor on the WHO Model List of Essential Medicines. By inhibiting PDE4, it elevates intracellular cyclic adenosine monophosphate (cAMP), down-regulating pro-inflammatory cytokine expression (TNF-alpha, IL-17, IL-23) while up-regulating anti-inflammatory IL-10. Indicated for moderate-to-severe plaque psoriasis in adults who are candidates for phototherapy or systemic therapy, and active psoriatic arthritis.

Clobetasol Propionate (0.05% w/w) is an ultra-high potency (Class I) topical synthetic corticosteroid on the WHO Model List of Essential Medicines. It binds to intracellular glucocorticoid receptors, down-regulating inflammatory cytokines (IL-1, IL-2, TNF-alpha) and inducing lipocortins to block phospholipase A2 and arachidonic acid cascade products. Indicated for short-term management of moderate-to-severe plaque psoriasis, recalcitrant dermatoses, lichen planus, and severe discoid lupus erythematosus.

Acitretin is an oral second-generation aromatic retinoid and the active acid metabolite of etretinate on the WHO Model List of Essential Medicines. It modulates cellular differentiation and proliferation in the epidermis, suppressing epidermal hyperkeratosis and parakeratosis. Indicated for severe extensive plaque psoriasis, pustular psoriasis, erythrodermic psoriasis, and severe disorders of keratinization (ichthyosis, Darier's disease).

Tofacitinib (2% w/w ointment) is a topical Janus kinase (JAK1/JAK3) inhibitor. It blocks intracellular JAK-STAT signaling pathways for multiple key inflammatory cytokines (IL-4, IL-13, IL-22, IL-31), rapidly reducing itch and clearing epidermal inflammation in inflammatory skin diseases without causing steroid-induced skin atrophy. Indicated for atopic dermatitis, alopecia areata, and plaque psoriasis.

Vitamin E Soft Gel Capsules (200mg, 400mg, 600mg) is an oral fat-soluble antioxidant (d-alpha-tocopheryl acetate) on the WHO Model List framework. It integrates into phospholipid cell membranes, where it traps peroxyl free radicals and halts the propagation of lipid peroxidation chain reactions, protecting polyunsaturated fatty acids in membranes, red blood cells, and vascular endothelial cells from oxidative injury. Indicated for vitamin E deficiency, supportive management of non-alcoholic fatty liver disease (NASH), peripheral neuropathy in abetalipoproteinemia, and adjuvant skin/hair health.

Vitamin C Formulations (500mg Chewable Tablets, 1000mg Effervescent Tablets with Vitamin D3 and Zinc, Injection) is an essential water-soluble antioxidant and cofactor on the WHO Model List of Essential Medicines. Ascorbic acid is a critical cofactor for prolyl and lysyl hydroxylase enzymes in collagen biosynthesis, carnitine synthesis, and norepinephrine synthesis; scavenges reactive oxygen species; enhances non-heme iron absorption; and boosts immune phagocytosis. Indicated for prevention and treatment of scurvy, immune support during respiratory infections, accelerated wound healing following surgery or burns, and nutritional antioxidant protection.

Tannic Acid Glycerin (27% w/v), Potassium Iodide, Iodine, Menthol, and Thymol Mouth Paint is a traditional astringent and antiseptic oral formulation. Tannic acid precipitates surface proteins on inflamed mucous membranes, forming a protective barrier that reduces bleeding, tightens lax spongy gums, and decreases exudation. Iodine and thymol exert antiseptic action against oral pathogens, while menthol provides soothing cooling pain relief. Indicated for bleeding gums, gingivitis, spongy gums, periodontitis, and painful aphthous lesions.

Hydrocortisone Acetate (1% w/w) is a low-potency (Class VII) topical corticosteroid on the WHO Model List of Essential Medicines. It represents the safest topical steroid for sensitive skin areas (face, intertriginous skin folds, groin) and pediatric patients, providing anti-inflammatory, anti-pruritic, and mild vasoconstrictive actions with minimal risk of skin thinning or systemic absorption. Indicated for mild eczema, facial dermatitis, intertrigo, insect bites, and anogenital pruritus.

Fluocinolone Acetonide / Fluocinonide is an intermediate-to-high potency fluorinated topical corticosteroid. It suppresses cutaneous inflammation and capillary permeability. Indicated for atopic dermatitis, severe contact dermatitis, and lichenified eczema.