OintmentClinical Overview
Tofacitinib (2% w/w ointment) is a topical Janus kinase (JAK1/JAK3) inhibitor. It blocks intracellular JAK-STAT signaling pathways for multiple key inflammatory cytokines (IL-4, IL-13, IL-22, IL-31), rapidly reducing itch and clearing epidermal inflammation in inflammatory skin diseases without causing steroid-induced skin atrophy. Indicated for atopic dermatitis, alopecia areata, and plaque psoriasis.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Apply a thin layer to affected skin areas twice daily. Wash hands after application. Avoid eyes and mouth.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Mild localized burning, folliculitis, headache, erythema. Rare/Severe: Secondary skin infections, contact dermatitis.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
For external cutaneous application only. Avoid application to actively infected skin lesions.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered dermatologist or qualified medical practitioner before initiating, altering, or substituting any topical or systemic dermatological treatment.
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