TabletsClinical Overview
Drotaverine Hydrochloride (80mg) and Mefenamic Acid (250mg) Tablets is a fixed-dose antispasmodic and non-steroidal anti-inflammatory (NSAID) combination. Drotaverine is an isoquinoline derivative that selectively inhibits phosphodiesterase-4 (PDE4), elevating intracellular cyclic AMP (cAMP) and causing rapid, powerful smooth muscle relaxation without anticholinergic side effects. Mefenamic acid inhibits cyclooxygenase (COX-1/COX-2), blocking pro-inflammatory and spasmogenic prostaglandin synthesis. Indicated for severe spasmodic dysmenorrhea, renal and ureteric colic, biliary colic, and acute spastic intestinal contractions.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally with food or a glass of milk to prevent gastric irritation, 1 tablet two to three times daily as needed during acute spasm episodes. Swallow whole.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Epigastric distress, nausea, dizziness, headache, heartburn, dry mouth. Rare/Severe: Peptic ulceration, gastrointestinal hemorrhage, renal impairment, bronchospasm, and transaminase elevations.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in active peptic ulcer disease, severe renal/hepatic impairment, and third-trimester pregnancy. Safe from anticholinergic effects like dry mouth and glaucoma exacerbation.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or gastrointestinal treatment recommendations. Always consult a registered gastroenterologist or qualified medical practitioner before initiating, altering, or discontinuing any gastrointestinal medication or digestive therapy.
Tranexamic Acid 500mg + Mefenamic Acid 250mg Tablets
Tranexamic Acid 500mg + Mefenamic Acid 250mg Tablets is an evidence-based cardiovascular and hemodynamic pharmaceutical formulation. It acts by modulating vascular smooth muscle tone, autonomic receptors, or fluid-electrolyte balance to manage cardiovascular disease.
Dicyclomine Hydrochloride 10mg + Mefenamic Acid 250mg Tablets
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Rabeprazole 20mg (Enteric Coated) + Levosulpiride 75mg (Sustained Release) Capsules
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Mefenamic Acid Suspension 100mg per 5ml
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