SuspensionClinical Overview
Mefenamic Acid Tablets (250mg, 500mg) and Suspension (100mg/5ml) is an oral fenamate NSAID on the WHO Model List framework. It exhibits a unique dual mechanism of action: it inhibits cyclooxygenase (COX-1/COX-2) to block prostaglandin synthesis, and directly antagonizes prostaglandin EP receptors on myometrial and vascular smooth muscle, providing superior relief from uterine hypercontractility and menorrhagia. Indicated for relief of primary dysmenorrhea, menorrhagia (heavy menstrual bleeding), mild-to-moderate postoperative and dental pain, and headache.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally with food or milk: 500 mg initially, followed by 250 mg every 6 hours as needed (maximum 1500 mg daily). For dysmenorrhea, initiate at the onset of bleeding and cramps, for a maximum of 2 to 3 days.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Diarrhea, dyspepsia, nausea, abdominal pain, headache, drowsiness. Rare/Severe: Autoimmune hemolytic anemia, severe steatorrhea/colitis, peptic ulceration, and acute interstitial nephritis.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Discontinue immediately if severe diarrhea or hemolytic anemia occurs. Treatment duration should not exceed 7 days for acute pain or 2-3 days for dysmenorrhea. Contraindicated in active peptic ulcer disease, inflammatory bowel disease, and renal impairment.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or analgesic treatment guidance. Always consult a registered physician or orthopedic specialist before taking pain relievers, anti-inflammatory medications, or anti-arthritic therapies.
Tranexamic Acid 500mg + Mefenamic Acid 250mg Tablets
Tranexamic Acid 500mg + Mefenamic Acid 250mg Tablets is an evidence-based cardiovascular and hemodynamic pharmaceutical formulation. It acts by modulating vascular smooth muscle tone, autonomic receptors, or fluid-electrolyte balance to manage cardiovascular disease.
Dicyclomine Hydrochloride 10mg + Mefenamic Acid 250mg Tablets
Dicyclomine Hydrochloride (10mg) and Mefenamic Acid (250mg) Tablets is a fixed-dose antispasmodic and fenamate NSAID combination. Dicyclomine relieves visceral smooth muscle spasms via antimuscarinic action and direct musculotropic relaxation; mefenamic acid inhibits cyclooxygenase and antagonizes prostaglandin receptors, eliminating pelvic pain and cramping. Indicated for severe spasmodic dysmenorrhea, intestinal colic, and spastic abdominal pain.
Rabeprazole 20mg (Enteric Coated) + Levosulpiride 75mg (Sustained Release) Capsules
Rabeprazole Sodium (20mg enteric-coated) and Levosulpiride (75mg sustained-release) combines a fast-acting proton pump inhibitor with a prokinetic and psychotropic benzamide. Rabeprazole rapidly suppresses gastric acid output, while levosulpiride selectively blocks dopamine D2 receptors and activates 5-HT4 receptors in the gastrointestinal tract, stimulating gastroduodenal motility and improving visceral hypersensitivity. Indicated for severe GERD, reflux esophagitis with delayed gastric emptying, non-ulcer dyspepsia, and gastroparesis.
Drotaverine Hydrochloride 80mg + Mefenamic Acid 250mg Tablets
Drotaverine Hydrochloride (80mg) and Mefenamic Acid (250mg) Tablets is a fixed-dose antispasmodic and non-steroidal anti-inflammatory (NSAID) combination. Drotaverine is an isoquinoline derivative that selectively inhibits phosphodiesterase-4 (PDE4), elevating intracellular cyclic AMP (cAMP) and causing rapid, powerful smooth muscle relaxation without anticholinergic side effects. Mefenamic acid inhibits cyclooxygenase (COX-1/COX-2), blocking pro-inflammatory and spasmogenic prostaglandin synthesis. Indicated for severe spasmodic dysmenorrhea, renal and ureteric colic, biliary colic, and acute spastic intestinal contractions.