Mefenamic Acid

Tranexamic Acid 500mg + Mefenamic Acid 250mg Tablets is an evidence-based cardiovascular and hemodynamic pharmaceutical formulation. It acts by modulating vascular smooth muscle tone, autonomic receptors, or fluid-electrolyte balance to manage cardiovascular disease.

Dicyclomine Hydrochloride (10mg) and Mefenamic Acid (250mg) Tablets is a fixed-dose antispasmodic and fenamate NSAID combination. Dicyclomine relieves visceral smooth muscle spasms via antimuscarinic action and direct musculotropic relaxation; mefenamic acid inhibits cyclooxygenase and antagonizes prostaglandin receptors, eliminating pelvic pain and cramping. Indicated for severe spasmodic dysmenorrhea, intestinal colic, and spastic abdominal pain.

Rabeprazole Sodium (20mg enteric-coated) and Levosulpiride (75mg sustained-release) combines a fast-acting proton pump inhibitor with a prokinetic and psychotropic benzamide. Rabeprazole rapidly suppresses gastric acid output, while levosulpiride selectively blocks dopamine D2 receptors and activates 5-HT4 receptors in the gastrointestinal tract, stimulating gastroduodenal motility and improving visceral hypersensitivity. Indicated for severe GERD, reflux esophagitis with delayed gastric emptying, non-ulcer dyspepsia, and gastroparesis.

Mefenamic Acid Tablets (250mg, 500mg) and Suspension (100mg/5ml) is an oral fenamate NSAID on the WHO Model List framework. It exhibits a unique dual mechanism of action: it inhibits cyclooxygenase (COX-1/COX-2) to block prostaglandin synthesis, and directly antagonizes prostaglandin EP receptors on myometrial and vascular smooth muscle, providing superior relief from uterine hypercontractility and menorrhagia. Indicated for relief of primary dysmenorrhea, menorrhagia (heavy menstrual bleeding), mild-to-moderate postoperative and dental pain, and headache.

Drotaverine Hydrochloride (80mg) and Mefenamic Acid (250mg) Tablets is a fixed-dose antispasmodic and non-steroidal anti-inflammatory (NSAID) combination. Drotaverine is an isoquinoline derivative that selectively inhibits phosphodiesterase-4 (PDE4), elevating intracellular cyclic AMP (cAMP) and causing rapid, powerful smooth muscle relaxation without anticholinergic side effects. Mefenamic acid inhibits cyclooxygenase (COX-1/COX-2), blocking pro-inflammatory and spasmogenic prostaglandin synthesis. Indicated for severe spasmodic dysmenorrhea, renal and ureteric colic, biliary colic, and acute spastic intestinal contractions.

Paracetamol / Acetaminophen (Tablets 500mg, 650mg, 1000mg; Oral Suspension 120mg, 125mg, 250mg per 5ml; Drops 100mg/ml) is a first-line non-opioid analgesic and antipyretic on the WHO Model List of Essential Medicines. It selectively inhibits central prostaglandin synthesis through peroxidase-dependent inhibition of COX enzymes in the brain and spinal cord, activates descending serotonergic inhibitory pathways, and resets the hypothalamic thermoregulatory center to reduce fever through cutaneous vasodilation and sweating. Unlike NSAIDs, it does NOT inhibit peripheral cyclooxygenase, causing zero gastric mucosal ulceration, platelet dysfunction, or renal vasoconstriction. Indicated as first-line therapy for mild-to-moderate pain (headache, toothache, dysmenorrhea, osteoarthritis) and fever of diverse etiologies.

Mefenamic Acid Tablets (250mg, 500mg) and Suspension (100mg/5ml) is an oral fenamate NSAID on the WHO Model List framework. It exhibits a unique dual mechanism of action: it inhibits cyclooxygenase (COX-1/COX-2) to block prostaglandin synthesis, and directly antagonizes prostaglandin EP receptors on myometrial and vascular smooth muscle, providing superior relief from uterine hypercontractility and menorrhagia. Indicated for relief of primary dysmenorrhea, menorrhagia (heavy menstrual bleeding), mild-to-moderate postoperative and dental pain, and headache.

Mefenamic Acid Tablets (250mg, 500mg) and Suspension (100mg/5ml) is an oral fenamate NSAID on the WHO Model List framework. It exhibits a unique dual mechanism of action: it inhibits cyclooxygenase (COX-1/COX-2) to block prostaglandin synthesis, and directly antagonizes prostaglandin EP receptors on myometrial and vascular smooth muscle, providing superior relief from uterine hypercontractility and menorrhagia. Indicated for relief of primary dysmenorrhea, menorrhagia (heavy menstrual bleeding), mild-to-moderate postoperative and dental pain, and headache.

Hyoscine Butylbromide (10mg) and Mefenamic Acid (250mg) Tablets combines a quaternary ammonium antimuscarinic antispasmodic with an NSAID analgesic. Hyoscine butylbromide exerts localized antispasmodic activity on gastrointestinal, biliary, and genitourinary smooth muscle without central sedation, while mefenamic acid inhibits prostaglandin synthesis. Indicated for severe spasmodic dysmenorrhea, acute abdominal colic, and renal colic.