SuspensionClinical Overview
Sucralfate (1g) and Oxetacaine (10mg) Suspension (per 10ml) combines a cytoprotective mucosal adherent with a potent local anesthetic. In the presence of gastric acid, sucralfate polymerizes into a viscous paste that selectively binds to positively charged proteinaceous exudates on ulcer craters, forming a protective physical barrier against acid, pepsin, and bile salts. Oxetacaine provides surface anesthesia to gastric and esophageal mucosa even in strongly acidic conditions (pH 1-2), delivering rapid relief from intense burning pain. Indicated for active gastric ulcers, duodenal ulcers, severe erosive esophagitis, and acute gastritis with severe epigastric pain.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Shake the bottle thoroughly before each dose. Take 10 mL orally four times daily, 1 hour before meals and at bedtime on an empty stomach. Do not take antacids within 30 minutes before or after sucralfate.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Constipation (due to aluminum), dry mouth, nausea, indigestion, glossal numbness (from oxetacaine). Rare/Severe: Aluminum accumulation/osteomalacia in renal failure, and bezoar formation in patients with gastroparesis.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Take on an empty stomach for proper mucosal polymerization. May decrease bioavailability of co-administered medications (quinolones, phenytoin, digoxin); space other drugs at least 2 hours apart. Caution in chronic renal failure due to aluminum absorption.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or gastrointestinal treatment recommendations. Always consult a registered gastroenterologist or qualified medical practitioner before initiating, altering, or discontinuing any gastrointestinal medication or digestive therapy.
Oxetacaine + Aluminium Hydroxide + Magnesium Hydroxide Suspension
Oxetacaine, Aluminium Hydroxide, and Magnesium Hydroxide Suspension is an anesthetic antacid combination. Aluminium and magnesium hydroxides provide balanced, nonsystemic neutralization of gastric hydrochloric acid, raising gastric pH and inhibiting peptic activity without causing rebound hypersecretion. Oxetacaine is a potent, non-irritating surface anesthetic that retains local anesthetic efficacy in strongly acidic environments (pH 1-2), producing rapid and long-lasting relief from acute burning ulcer and esophagitis pain. Indicated for severe acute gastritis, esophagitis, heartburn, and peptic ulcer pain.
Sucralfate Suspension 500mg per 5ml
Sucralfate Suspension (500mg/5ml) is an oral basic aluminum salt of sucrose octasulfate on the WHO Model List of Essential Medicines. Under acidic conditions (pH < 4), it polymerizes into an insoluble, polyanionic gel that adheres tenaciously to ulcerated mucosal tissue, protecting the ulcer crater from gastric acid, pepsin, and bile acids while stimulating endogenous prostaglandin synthesis and epidermal growth factor. Indicated for active duodenal ulcers, gastric ulcers, stress ulcer prophylaxis, and reflux esophagitis.
Megaldrate 540mg + Simethicone 50mg + Oxetacaine 10mg Oral Suspension
Magaldrate (400mg/540mg) and Simethicone (20mg/50mg, with or without Oxetacaine 10mg) Oral Suspension is a balanced antacid, antiflatulent, and mucosal anesthetic formulation. Magaldrate (hydroxymagnesium aluminate complex) reacts rapidly with gastric acid to buffer intragastric pH to the ideal 3.0-5.0 range, neutralizing acid without causing acid rebound. Simethicone breaks mucosal gas bubbles to relieve bloating. Oxetacaine (when present) provides prompt topical anesthesia on inflamed gastric and esophageal mucosa. Indicated for hyperacidity, heartburn, reflux esophagitis, gastritis, and peptic ulcer pain with flatulence.
Lignocaine 4% w/w + Metronidazole 1% w/w + Sucralfate 7% w/w Cream
Lignocaine (4% w/w), Metronidazole (1% w/w), and Sucralfate (7% w/w) Cream is a specialized topical rectal formulation. Lignocaine produces rapid local analgesia by blocking voltage-gated sodium channels. Metronidazole provides topical antimicrobial activity against anaerobic rectal flora, reducing secondary infection and inflammation. Sucralfate forms an adhesive barrier over mucosal fissures and hemorrhoidal ulcers, accelerating re-epithelialization and tissue healing. Indicated for acute and chronic anal fissures, painful thrombosed hemorrhoids, and post-hemorrhoidectomy wound healing.