Oxetacaine

Oxetacaine, Aluminium Hydroxide, and Magnesium Hydroxide Suspension is an anesthetic antacid combination. Aluminium and magnesium hydroxides provide balanced, nonsystemic neutralization of gastric hydrochloric acid, raising gastric pH and inhibiting peptic activity without causing rebound hypersecretion. Oxetacaine is a potent, non-irritating surface anesthetic that retains local anesthetic efficacy in strongly acidic environments (pH 1-2), producing rapid and long-lasting relief from acute burning ulcer and esophagitis pain. Indicated for severe acute gastritis, esophagitis, heartburn, and peptic ulcer pain.

Sucralfate (1g) and Oxetacaine (10mg) Suspension (per 10ml) combines a cytoprotective mucosal adherent with a potent local anesthetic. In the presence of gastric acid, sucralfate polymerizes into a viscous paste that selectively binds to positively charged proteinaceous exudates on ulcer craters, forming a protective physical barrier against acid, pepsin, and bile salts. Oxetacaine provides surface anesthesia to gastric and esophageal mucosa even in strongly acidic conditions (pH 1-2), delivering rapid relief from intense burning pain. Indicated for active gastric ulcers, duodenal ulcers, severe erosive esophagitis, and acute gastritis with severe epigastric pain.

Magaldrate (400mg/540mg) and Simethicone (20mg/50mg, with or without Oxetacaine 10mg) Oral Suspension is a balanced antacid, antiflatulent, and mucosal anesthetic formulation. Magaldrate (hydroxymagnesium aluminate complex) reacts rapidly with gastric acid to buffer intragastric pH to the ideal 3.0-5.0 range, neutralizing acid without causing acid rebound. Simethicone breaks mucosal gas bubbles to relieve bloating. Oxetacaine (when present) provides prompt topical anesthesia on inflamed gastric and esophageal mucosa. Indicated for hyperacidity, heartburn, reflux esophagitis, gastritis, and peptic ulcer pain with flatulence.