Oral Care & Stomatologicals

Chlorhexidine Gluconate Mouthwash (0.2% w/v; with or without Sodium Fluoride 0.05% and Zinc Chloride 0.09%) is an oral broad-spectrum antiseptic and anti-plaque rinse on the WHO Model List of Essential Medicines. As a cationic bisbiguanide, chlorhexidine binds tenaciously to bacterial cell walls and oral pellicles, adsorbing to oral surfaces and releasing slowly over 12 hours (substantivity) to provide sustained bactericidal and bacteriostatic activity against gram-positive and gram-negative pathogens. Indicated for prevention and treatment of gingivitis, dental plaque reduction, aphthous ulcers, post-periodontal surgery hygiene, and prevention of ventilator-associated pneumonia in ICU patients.

Omeprazole Gastro-Resistant Capsules (20mg) is a prototypical proton pump inhibitor on the WHO Model List of Essential Medicines. It enters parietal cell canaliculi as a prodrug where acidic pH converts it to a tetracyclic sulfenamide that permanently inactivates H+/K+-ATPase pumps. Indicated for duodenal ulcers, benign gastric ulcers, reflux esophagitis, maintenance therapy of healed erosive esophagitis, and H. pylori eradication (as part of triple therapy).

Mouth Ulcer Gel (Choline Salicylate 8.7%-9% w/w, Benzalkonium Chloride 0.01% w/w, with or without Lignocaine 2% w/w) is a topical analgesic, anti-inflammatory, and antiseptic oral gel on the PMBI formulary. Choline salicylate is a topically absorbed non-steroidal anti-inflammatory that inhibits cyclooxygenase enzymes to relieve throbbing ulcer pain and swelling. Lignocaine produces rapid surface local anesthesia by blocking mucosal voltage-gated sodium channels. Benzalkonium chloride acts as a cationic surfactant bactericide, preventing secondary infection. Indicated for aphthous mouth ulcers, canker sores, denture sores, orthodontic abrasions, and herpes labialis irritation.

Mouth Ulcer Gel (Choline Salicylate 8.7%-9% w/w, Benzalkonium Chloride 0.01% w/w, with or without Lignocaine 2% w/w) is a topical analgesic, anti-inflammatory, and antiseptic oral gel on the PMBI formulary. Choline salicylate is a topically absorbed non-steroidal anti-inflammatory that inhibits cyclooxygenase enzymes to relieve throbbing ulcer pain and swelling. Lignocaine produces rapid surface local anesthesia by blocking mucosal voltage-gated sodium channels. Benzalkonium chloride acts as a cationic surfactant bactericide, preventing secondary infection. Indicated for aphthous mouth ulcers, canker sores, denture sores, orthodontic abrasions, and herpes labialis irritation.

Clotrimazole Mouth Paint (1% w/v) is a topical imidazole antifungal solution on the WHO Model List of Essential Medicines. It inhibits fungal cytochrome P450 14-alpha-demethylase, halting ergosterol biosynthesis and disrupting fungal cytoplasmic membrane permeability in Candida species. Indicated for treatment of oral candidiasis (oral thrush), candidal stomatitis, and denture-induced stomatitis.

Desensitizing Toothpastes (Potassium Nitrate 5% w/w with Sodium Monofluorophosphate, or Strontium Chloride Hexahydrate 10% w/w) is a therapeutic dental dentifrice on the PMBI formulary. Potassium nitrate diffuses through open dentinal tubules to increase extracellular potassium ion concentration, depolarizing sensory nerve endings in the dental pulp and blocking action potential transmission to provide lasting relief from dentin hypersensitivity pain (cold, hot, sweet, tactile triggers). Strontium chloride physically occludes open dentinal tubules. Fluoride remineralizes enamel. Indicated for dentinal hypersensitivity and prevention of dental caries.

Tannic Acid Glycerin (27% w/v), Potassium Iodide, Iodine, Menthol, and Thymol Mouth Paint is a traditional astringent and antiseptic oral formulation. Tannic acid precipitates surface proteins on inflamed mucous membranes, forming a protective barrier that reduces bleeding, tightens lax spongy gums, and decreases exudation. Iodine and thymol exert antiseptic action against oral pathogens, while menthol provides soothing cooling pain relief. Indicated for bleeding gums, gingivitis, spongy gums, periodontitis, and painful aphthous lesions.

Chlorhexidine Gluconate Mouthwash (0.2% w/v; with or without Sodium Fluoride 0.05% and Zinc Chloride 0.09%) is an oral broad-spectrum antiseptic and anti-plaque rinse on the WHO Model List of Essential Medicines. As a cationic bisbiguanide, chlorhexidine binds tenaciously to bacterial cell walls and oral pellicles, adsorbing to oral surfaces and releasing slowly over 12 hours (substantivity) to provide sustained bactericidal and bacteriostatic activity against gram-positive and gram-negative pathogens. Indicated for prevention and treatment of gingivitis, dental plaque reduction, aphthous ulcers, post-periodontal surgery hygiene, and prevention of ventilator-associated pneumonia in ICU patients.

Mouth Ulcer Gel (Choline Salicylate 8.7%-9% w/w, Benzalkonium Chloride 0.01% w/w, with or without Lignocaine 2% w/w) is a topical analgesic, anti-inflammatory, and antiseptic oral gel on the PMBI formulary. Choline salicylate is a topically absorbed non-steroidal anti-inflammatory that inhibits cyclooxygenase enzymes to relieve throbbing ulcer pain and swelling. Lignocaine produces rapid surface local anesthesia by blocking mucosal voltage-gated sodium channels. Benzalkonium chloride acts as a cationic surfactant bactericide, preventing secondary infection. Indicated for aphthous mouth ulcers, canker sores, denture sores, orthodontic abrasions, and herpes labialis irritation.

Desensitizing Toothpastes (Potassium Nitrate 5% w/w with Sodium Monofluorophosphate, or Strontium Chloride Hexahydrate 10% w/w) is a therapeutic dental dentifrice on the PMBI formulary. Potassium nitrate diffuses through open dentinal tubules to increase extracellular potassium ion concentration, depolarizing sensory nerve endings in the dental pulp and blocking action potential transmission to provide lasting relief from dentin hypersensitivity pain (cold, hot, sweet, tactile triggers). Strontium chloride physically occludes open dentinal tubules. Fluoride remineralizes enamel. Indicated for dentinal hypersensitivity and prevention of dental caries.

Desensitizing Toothpastes (Potassium Nitrate 5% w/w with Sodium Monofluorophosphate, or Strontium Chloride Hexahydrate 10% w/w) is a therapeutic dental dentifrice on the PMBI formulary. Potassium nitrate diffuses through open dentinal tubules to increase extracellular potassium ion concentration, depolarizing sensory nerve endings in the dental pulp and blocking action potential transmission to provide lasting relief from dentin hypersensitivity pain (cold, hot, sweet, tactile triggers). Strontium chloride physically occludes open dentinal tubules. Fluoride remineralizes enamel. Indicated for dentinal hypersensitivity and prevention of dental caries.