TabletsClinical Overview
Norfloxacin (400mg) and Tinidazole (600mg) Tablets is a fixed-dose broad-spectrum antibacterial and antiprotozoal combination. Norfloxacin is a second-generation fluoroquinolone that inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV. Tinidazole is a second-generation nitroimidazole that causes DNA strand breakage in anaerobic bacteria and protozoa. Indicated for acute infectious diarrhea, amoebic dysentery (Entamoeba histolytica), mixed bacterial-protozoal enteritis, and giardiasis.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally 1 tablet twice daily with a full glass of water, 1 hour before or 2 hours after meals. Complete the full 5-day course. Strictly avoid alcohol during therapy and for 3 days after completion.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Metallic taste, nausea, epigastric distress, headache, dizziness, flatulence. Rare/Severe: Tendinitis/tendon rupture (fluoroquinolone warning), peripheral neuropathy, disulfiram-like reaction with alcohol, and QT prolongation.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Schedule H1 Prescription Antibiotic: Do NOT consume alcohol during and for 72 hours after therapy (severe disulfiram reaction). Contraindicated in patients with known hypersensitivity to fluoroquinolones or nitroimidazoles, history of tendon disorders, and pregnancy.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or gastrointestinal treatment recommendations. Always consult a registered gastroenterologist or qualified medical practitioner before initiating, altering, or discontinuing any gastrointestinal medication or digestive therapy.
Ciprofloxacin 250mg + Tinidazole 300mg Tablets
Ciprofloxacin and Tinidazole is a broad-spectrum dual antimicrobial combination. Ciprofloxacin, a fluoroquinolone, inhibits bacterial DNA gyrase and topoisomerase IV, targeting aerobic Gram-negative and Gram-positive bacteria, while tinidazole, a second-generation nitroimidazole, generates free nitro-radicals that damage protozoal and anaerobic DNA. Indicated for mixed aerobic-anaerobic bacterial and protozoal infections, including amoebiasis, giardiasis, bacterial dysentery, pelvic inflammatory disease, and dental abscesses.
Ciprofloxacin 500mg + Tinidazole 600mg Tablets
Ciprofloxacin and Tinidazole is a broad-spectrum dual antimicrobial combination. Ciprofloxacin, a fluoroquinolone, inhibits bacterial DNA gyrase and topoisomerase IV, targeting aerobic Gram-negative and Gram-positive bacteria, while tinidazole, a second-generation nitroimidazole, generates free nitro-radicals that damage protozoal and anaerobic DNA. Indicated for mixed aerobic-anaerobic bacterial and protozoal infections, including amoebiasis, giardiasis, bacterial dysentery, pelvic inflammatory disease, and dental abscesses.
Norfloxacin Tablets 400 mg
Norfloxacin is a fluoroquinolone antibacterial agent that acts by inhibiting bacterial DNA gyrase. Due to limited systemic absorption and high concentrations achieved in urine and the gastrointestinal tract, its clinical utility is focused specifically on urinary tract infections and enteric pathogens. Indicated for uncomplicated and complicated urinary tract infections, bacterial prostatitis, and acute bacterial gastroenteritis (traveler's diarrhea).
Tinidazole Tablets 300 mg
Tinidazole is a second-generation 5-nitroimidazole antimicrobial agent with a significantly longer elimination half-life (12-14 hours) than metronidazole, allowing once-daily dosing. It diffuses into microorganisms where its nitro group is reduced, creating free radicals that cause DNA strand breakage. Indicated for intestinal and hepatic amoebiasis, giardiasis, trichomoniasis, bacterial vaginosis, and prevention/treatment of postoperative anaerobic infections.