TabletsClinical Overview
Sodium Picosulphate Tablets (10mg) is an oral prodrug stimulant contact laxative on the WHO Model List framework. It passes unabsorbed through the stomach and small intestine to the colon, where bacterial sulfatases hydrolyze it to the active free diphenol metabolite (BHPM). This metabolite stimulates mucosal sensory nerve endings to induce strong colonic propulsive contractions within 6 to 12 hours. Indicated for short-term management of constipation and colon preparation prior to colonoscopy.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally 5 to 10 mg at bedtime with a full glass of water. Swallow whole. Effect typically occurs the following morning.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Abdominal cramps, diarrhea, nausea, dizziness. Rare/Severe: Dehydration, hypokalemia, and secondary hyperaldosteronism with excessive chronic use.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in severe dehydration, mechanical bowel obstruction, ileus, acute surgical abdomen, and toxic megacolon. Limit continuous usage to under 5 days.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or gastrointestinal treatment recommendations. Always consult a registered gastroenterologist or qualified medical practitioner before initiating, altering, or discontinuing any gastrointestinal medication or digestive therapy.
