Clinical Overview
Deflazacort (30mg) and Tamsulosin (0.4mg) Tablets is a specialized medical expulsive therapy (MET) combination. Tamsulosin blocks alpha-1D receptors located predominantly in the lower third of the ureter and ureterovesical junction (UVJ), inhibiting ureteral smooth muscle spasm and dilating the ureteral lumen. Deflazacort is an oxazoline glucocorticoid that exerts potent anti-inflammatory and anti-edematous action around the impacted stone site, reducing localized mucosal swelling and pain. Indicated for medical expulsive therapy of distal ureteral calculi (stones measuring 5 to 10 mm) to accelerate spontaneous stone passage and reduce surgical intervention.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once daily in the morning with food for a short course of 7 to 14 days, as directed by the urologist. Drink plenty of water (at least 2.5 to 3 liters daily) to promote diuresis and stone expulsion.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Dizziness, headache, retrograde ejaculation, transient epigastric discomfort, insomnia, fluid retention. Rare/Severe: Orthostatic hypotension, hyperglycemia, peptic ulceration, and stone impaction requiring emergency stenting.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Short-term treatment only (7-14 days). Discontinue immediately and seek emergency urological evaluation if fever, chills, intractable colic pain, or anuria develops (indicative of obstructive urosepsis). Caution in diabetes and active peptic ulcer disease.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, nephrological diagnosis, or urological treatment recommendations. Always consult a registered nephrologist, urologist, or qualified medical practitioner before initiating, modifying, or discontinuing any kidney or urinary tract medication.