Metronidazole

Metronidazole is a synthetic nitroimidazole antimicrobial on the WHO Model List of Essential Medicines. It enters microbial cells via passive diffusion, where its nitro group is reduced by microbial ferredoxin to generate cytotoxic nitro radicals that disrupt helical DNA structure, leading to cell death. Highly effective against obligate anaerobes (Bacteroides, Clostridium) and protozoa (Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis). Indicated for amoebiasis, giardiasis, trichomoniasis, bacterial vaginosis, anaerobic surgical sepsis, and H. pylori eradication.

Metronidazole is a synthetic nitroimidazole antimicrobial on the WHO Model List of Essential Medicines. It enters microbial cells via passive diffusion, where its nitro group is reduced by microbial ferredoxin to generate cytotoxic nitro radicals that disrupt helical DNA structure, leading to cell death. Highly effective against obligate anaerobes (Bacteroides, Clostridium) and protozoa (Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis). Indicated for amoebiasis, giardiasis, trichomoniasis, bacterial vaginosis, anaerobic surgical sepsis, and H. pylori eradication.

Metronidazole is a synthetic nitroimidazole antimicrobial on the WHO Model List of Essential Medicines. It enters microbial cells via passive diffusion, where its nitro group is reduced by microbial ferredoxin to generate cytotoxic nitro radicals that disrupt helical DNA structure, leading to cell death. Highly effective against obligate anaerobes (Bacteroides, Clostridium) and protozoa (Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis). Indicated for amoebiasis, giardiasis, trichomoniasis, bacterial vaginosis, anaerobic surgical sepsis, and H. pylori eradication.

Chlorhexidine Gluconate 1% , Metronidazole 1% and Lidocaine 2% dental Gel is an evidence-based dermatological formulation. It acts by delivering targeted active therapeutic ingredients to cutaneous lesions to relieve skin pathology, restore barrier integrity, and manage dermatoses.

Metronidazole (1% ) + Povidone Iodine (5% ) Ointment is an evidence-based dermatological formulation. It acts by delivering targeted active therapeutic ingredients to cutaneous lesions to relieve skin pathology, restore barrier integrity, and manage dermatoses.

Lignocaine (4% w/w), Metronidazole (1% w/w), and Sucralfate (7% w/w) Cream is a specialized topical rectal formulation. Lignocaine produces rapid local analgesia by blocking voltage-gated sodium channels. Metronidazole provides topical antimicrobial activity against anaerobic rectal flora, reducing secondary infection and inflammation. Sucralfate forms an adhesive barrier over mucosal fissures and hemorrhoidal ulcers, accelerating re-epithelialization and tissue healing. Indicated for acute and chronic anal fissures, painful thrombosed hemorrhoids, and post-hemorrhoidectomy wound healing.

Mupirocin (2% w/w ointment) is a naturally derived antibiotic produced by Pseudomonas fluorescens on the WHO Model List of Essential Medicines. It reversibly binds specifically to bacterial isoleucyl-tRNA synthetase, completely arresting RNA and protein synthesis with zero cross-resistance to other antibiotic classes. Displays potent bactericidal activity against MRSA, MSSA, and Streptococcus pyogenes. Indicated for impetigo, traumatic skin lesions secondarily infected by S. aureus, and eradication of nasal MRSA carriage.

Ofloxacin and Metronidazole oral suspension is a dual antimicrobial formulation for mixed paediatric and adult gastrointestinal and systemic infections. Ofloxacin inhibits bacterial DNA gyrase, while metronidazole disrupts anaerobic and protozoal helical DNA structure. Indicated for bacterial and amoebic diarrhea, dysentery, giardiasis, and mixed aerobic-anaerobic infections.