TabletsTablets
Schedule H (Prescription Required)Broad-Spectrum AntibioticsCode: 202

Metronidazole Tablets 400mg

Generic Formulation:Metronidazole Tablets IP 400mg
Pack Size:10's
Common Commercial Brand Equivalents:Market reference only
Jan Aushadhi MRP
₹7.22
Brand Estimate*
₹15.39
Estimated Savings:₹8.17 (53% saved)
Find a Kendra Near You
*Statutory price across 21,118 listed Kendras
Clinical InformationReport Error

Clinical Overview

Metronidazole is a synthetic nitroimidazole antimicrobial on the WHO Model List of Essential Medicines. It enters microbial cells via passive diffusion, where its nitro group is reduced by microbial ferredoxin to generate cytotoxic nitro radicals that disrupt helical DNA structure, leading to cell death. Highly effective against obligate anaerobes (Bacteroides, Clostridium) and protozoa (Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis). Indicated for amoebiasis, giardiasis, trichomoniasis, bacterial vaginosis, anaerobic surgical sepsis, and H. pylori eradication.

Active Pharmaceutical Ingredients

AI-assistedClinical summary synthesized from pharmacopoeial references (CDSCO, WHO EML, IP/BP/USP). Not clinician-reviewed. Drug code 202.Report inaccuracy

Usage Guidelines

Swallow whole with a full glass of water with or immediately after meals to reduce stomach irritation. Do not crush. Completely avoid all alcohol and ethanol-containing medications during treatment and for at least 48 hours post-treatment. Complete the full course.

General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.

Possible Side Effects

Common: Metallic/bitter taste in mouth, nausea, epigastric distress, headache, anorexia, dark reddish-brown urine. Rare/Severe: Peripheral neuropathy, encephalopathy/cerebellar ataxia, seizures, Disulfiram-like ethanol reaction, and neutropenia.

*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.

Precautions & Warnings

Strict warning against alcohol: causes severe disulfiram-like reactions (flushing, nausea, vomiting, tachycardia, hypotension). Contraindicated in patients with severe hepatic failure or first-trimester pregnancy in trichomoniasis. Prolonged therapy requires monitoring for peripheral neuropathy.

Schedule H (Prescription Required)

This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.

Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.