Clinical Overview
Ofloxacin and Metronidazole oral suspension is a dual antimicrobial formulation for mixed paediatric and adult gastrointestinal and systemic infections. Ofloxacin inhibits bacterial DNA gyrase, while metronidazole disrupts anaerobic and protozoal helical DNA structure. Indicated for bacterial and amoebic diarrhea, dysentery, giardiasis, and mixed aerobic-anaerobic infections.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Shake the suspension bottle well before every use. Measure dose using the calibrated measuring cup provided. Administer with or after food. Keep patient well hydrated with oral rehydration solution (ORS). Do not consume alcohol during or for 48 hours after treatment.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Nausea, metallic taste, dark reddish-brown urine (harmless), abdominal cramps, headache. Rare/Severe: Tendonitis, peripheral neuropathy, seizures, encephalopathy, and pseudomembranous colitis.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Avoid alcohol completely due to disulfiram-like reactions. Contraindicated in first trimester of pregnancy and patients with neurological disorders. Discontinue if numbness, tingling, or tendon pain occurs.
Schedule H1 (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Ofloxacin 200mg + Ornidazole 500mg Tablets
Ofloxacin and Ornidazole is a broad-spectrum fixed-dose antimicrobial combination pairing a fluoroquinolone with a nitroimidazole. Ofloxacin halts bacterial DNA multiplication, while ornidazole damages microbial DNA through free nitro radicals, eradicating anaerobes and protozoa. Indicated for mixed bacterial and protozoal gastroenteritis, amoebic dysentery, pelvic inflammatory disease, dental infections, and post-surgical abdominal sepsis.
Ofloxacin Tablets 200mg
Ofloxacin is a synthetic fluoroquinolone bactericidal antibiotic. It acts by inhibiting bacterial DNA gyrase and topoisomerase IV, preventing bacterial DNA replication and repair. Broad-spectrum activity encompasses Gram-negative bacteria, Chlamydia trachomatis, Mycoplasma, and Mycobacterium tuberculosis (second-line). Indicated for acute exacerbations of chronic bronchitis, community-acquired pneumonia, uncomplicated urethral and cervical gonorrhoea, pelvic inflammatory disease, and complicated UTIs.
Ofloxacin Tablets 400mg
Ofloxacin is a synthetic fluoroquinolone bactericidal antibiotic. It acts by inhibiting bacterial DNA gyrase and topoisomerase IV, preventing bacterial DNA replication and repair. Broad-spectrum activity encompasses Gram-negative bacteria, Chlamydia trachomatis, Mycoplasma, and Mycobacterium tuberculosis (second-line). Indicated for acute exacerbations of chronic bronchitis, community-acquired pneumonia, uncomplicated urethral and cervical gonorrhoea, pelvic inflammatory disease, and complicated UTIs.
Metronidazole Infusion 500 mg
Metronidazole is a synthetic nitroimidazole antimicrobial on the WHO Model List of Essential Medicines. It enters microbial cells via passive diffusion, where its nitro group is reduced by microbial ferredoxin to generate cytotoxic nitro radicals that disrupt helical DNA structure, leading to cell death. Highly effective against obligate anaerobes (Bacteroides, Clostridium) and protozoa (Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis). Indicated for amoebiasis, giardiasis, trichomoniasis, bacterial vaginosis, anaerobic surgical sepsis, and H. pylori eradication.