Clinical Overview
Metronidazole is a synthetic nitroimidazole antimicrobial on the WHO Model List of Essential Medicines. It enters microbial cells via passive diffusion, where its nitro group is reduced by microbial ferredoxin to generate cytotoxic nitro radicals that disrupt helical DNA structure, leading to cell death. Highly effective against obligate anaerobes (Bacteroides, Clostridium) and protozoa (Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis). Indicated for amoebiasis, giardiasis, trichomoniasis, bacterial vaginosis, anaerobic surgical sepsis, and H. pylori eradication.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Administered by a licensed healthcare professional by continuous or intermittent intravenous infusion at an approximate rate of 5 mL/minute (over 20-30 minutes). Not for direct IV push.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Metallic/bitter taste in mouth, nausea, epigastric distress, headache, anorexia, dark reddish-brown urine. Rare/Severe: Peripheral neuropathy, encephalopathy/cerebellar ataxia, seizures, Disulfiram-like ethanol reaction, and neutropenia.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Strict warning against alcohol: causes severe disulfiram-like reactions (flushing, nausea, vomiting, tachycardia, hypotension). Contraindicated in patients with severe hepatic failure or first-trimester pregnancy in trichomoniasis. Prolonged therapy requires monitoring for peripheral neuropathy.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Metronidazole Tablets 200mg
Metronidazole is a synthetic nitroimidazole antimicrobial on the WHO Model List of Essential Medicines. It enters microbial cells via passive diffusion, where its nitro group is reduced by microbial ferredoxin to generate cytotoxic nitro radicals that disrupt helical DNA structure, leading to cell death. Highly effective against obligate anaerobes (Bacteroides, Clostridium) and protozoa (Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis). Indicated for amoebiasis, giardiasis, trichomoniasis, bacterial vaginosis, anaerobic surgical sepsis, and H. pylori eradication.
Metronidazole Tablets 400mg
Metronidazole is a synthetic nitroimidazole antimicrobial on the WHO Model List of Essential Medicines. It enters microbial cells via passive diffusion, where its nitro group is reduced by microbial ferredoxin to generate cytotoxic nitro radicals that disrupt helical DNA structure, leading to cell death. Highly effective against obligate anaerobes (Bacteroides, Clostridium) and protozoa (Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis). Indicated for amoebiasis, giardiasis, trichomoniasis, bacterial vaginosis, anaerobic surgical sepsis, and H. pylori eradication.
Chlorhexidine Gluconate 1% , Metronidazole 1% and Lidocaine 2% dental Gel
Chlorhexidine Gluconate 1% , Metronidazole 1% and Lidocaine 2% dental Gel is an evidence-based dermatological formulation. It acts by delivering targeted active therapeutic ingredients to cutaneous lesions to relieve skin pathology, restore barrier integrity, and manage dermatoses.
Metronidazole (1% ) + Povidone Iodine (5% ) Ointment
Metronidazole (1% ) + Povidone Iodine (5% ) Ointment is an evidence-based dermatological formulation. It acts by delivering targeted active therapeutic ingredients to cutaneous lesions to relieve skin pathology, restore barrier integrity, and manage dermatoses.