Oncology & Critical CarePart of Oncology & Critical Care
1 Formulations1 Rx0 OTC

Antidotes & Supportive Oncology

Leucovorin, mesna, and bisphosphonates for chemotherapy rescue and bone metastases. All formulations listed are procured under PMBI with verified WHO-GMP standard compliance.

Formulation & Pricing Breakdown0 priced
View details
Formulations1Subcategory medicines
With Listed Price0Active MRP registered
Prescription (Rx)1Valid prescription required
Over The Counter0Dispensed OTC at Kendras
PMBI quality-certified formulations manufactured under WHO-GMP compliance.
Other Divisions in Oncology & Critical Care:
Chemotherapy(35)Targeted Therapy(38)Hormone Oncology(14)Immunosuppressants(14)Hematology(3)Supportive Oncology(1)Other Oncology(1)All Oncology & Critical Care

Antidotes & Supportive Oncology Formulations (1)

Find Nearby Kendra
⚕ Rx OnlyAntidotes & Supportive Oncology

Leucovorin Calcium Tablets 15mg

Tablets
10's

Leucovorin Calcium / Folinic Acid Tablets (15mg) is the 5-formyl derivative of tetrahydrofolic acid (FH4) on the WHO Model List of Essential Medicines. It bypasses the enzymatic block created by dihydrofolate reductase (DHFR) inhibitors (such as methotrexate), directly entering folate cofactor pools to rescue normal host tissues from lethal toxicity ("Leucovorin Rescue"). Concurrently, in 5-fluorouracil chemotherapy, leucovorin stabilizes the ternary binding complex with thymidylate synthase, markedly enhancing 5-FU cytotoxicity. Indicated for rescue therapy following high-dose methotrexate chemotherapy, accidental methotrexate overdose, and potentiation of 5-FU in metastatic colorectal carcinoma.

Price on request
Leucovorin

Statutory Medical Guidance

All products listed are official PMBI-procured generic drugs and surgical consumables. Schedule H formulations require a valid doctor's prescription for dispensing at Jan Aushadhi Kendras. Always consult a certified healthcare professional before starting or altering any pharmaceutical therapy.