TabletsClinical Overview
Diclofenac Sodium/Potassium Tablets (50mg Gastro-Resistant, 75mg/100mg Prolonged Release) is an oral phenylacetic acid non-steroidal anti-inflammatory drug (NSAID) on the WHO Model List of Essential Medicines. It potently inhibits both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, halting prostaglandin synthesis, and also reduces intracellular concentrations of free arachidonic acid in leukocytes. Potassium salt provides rapid dissolution and quick pain relief; sodium prolonged-release provides steady 24-hour therapeutic coverage. Indicated for relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute musculoskeletal disorders, and acute migraine attacks.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally with food or milk with a full glass of water: 50 mg two to three times daily, or 75-100 mg prolonged-release tablet once daily. Swallow whole; do NOT chew or crush. Remain upright for 15-30 minutes after taking.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Epigastric distress, heartburn, nausea, diarrhea, dizziness, headache, edema. Rare/Severe: Peptic ulceration and gastrointestinal hemorrhage, myocardial infarction, stroke, acute kidney injury, and drug-induced hepatotoxicity.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black Box Warning: Cardiovascular thrombotic risk and gastrointestinal bleeding/ulceration. Lowest effective dose for the shortest possible duration should be used. Contraindicated in active peptic ulcer disease, CABG surgery, severe congestive heart failure, and third-trimester pregnancy.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or analgesic treatment guidance. Always consult a registered physician or orthopedic specialist before taking pain relievers, anti-inflammatory medications, or anti-arthritic therapies.
Chlorzoxazone 500mg + Diclofenac 50mg + Paracetamol 325mg Tablets
Paracetamol (325mg/500mg) and Chlorzoxazone (250mg) Tablets is a centrally acting skeletal muscle relaxant and analgesic combination. Chlorzoxazone inhibits multi-synaptic reflex arcs in the spinal cord and subcortical areas of the brain, relieving painful skeletal muscle spasms. Paracetamol acts centrally to alleviate associated pain and discomfort. Indicated for acute, painful musculoskeletal conditions, muscle spasms, lumbago, torticollis, and strain/sprain trauma.
Diclofenac Gel 1.16% (Diclofenac Diethylamine)
Diclofenac Gel 1.16% (Diclofenac Diethylamine) is an evidence-based dermatological formulation. It acts by delivering targeted active therapeutic ingredients to cutaneous lesions to relieve skin pathology, restore barrier integrity, and manage dermatoses.
Diclofenac Sodium Prolonged Release Tablets 100 mg
Diclofenac Sodium/Potassium Tablets (50mg Gastro-Resistant, 75mg/100mg Prolonged Release) is an oral phenylacetic acid non-steroidal anti-inflammatory drug (NSAID) on the WHO Model List of Essential Medicines. It potently inhibits both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, halting prostaglandin synthesis, and also reduces intracellular concentrations of free arachidonic acid in leukocytes. Potassium salt provides rapid dissolution and quick pain relief; sodium prolonged-release provides steady 24-hour therapeutic coverage. Indicated for relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute musculoskeletal disorders, and acute migraine attacks.
Diclofenac Sodium Injection 25mg per ml
Diclofenac Sodium Injection (25mg/ml, 75mg/3ml) is a parenteral phenylacetic acid NSAID on the WHO Model List of Essential Medicines. It potently inhibits COX-1 and COX-2 enzymes to block prostaglandin synthesis. Indicated for acute severe pain, renal colic, biliary colic, acute postoperative pain, and severe trauma.