TabletsClinical Overview
Aceclofenac Tablets (100mg, 200mg Sustained Release) is an oral phenylacetic acid-derivative non-steroidal anti-inflammatory drug (NSAID) on the WHO Model List framework. It exhibits preferential inhibition of the COX-2 isoenzyme over COX-1, dramatically reducing synthesis of pro-inflammatory cytokines (IL-1beta, TNF-alpha) and PGE2, while stimulating synthesis of extracellular cartilage matrix components (glycosaminoglycans) in articular cartilage. Indicated for symptomatic relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute musculoskeletal pain.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally with or after meals with a glass of water: 100 mg twice daily, or 200 mg sustained-release tablet once daily swallowed whole. Do not crush or chew sustained-release formulations.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Dyspepsia, epigastric discomfort, nausea, diarrhea, dizziness. Rare/Severe: Peptic ulceration, gastrointestinal hemorrhage, myocardial infarction, stroke, and hepatotoxicity.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black Box Warning: NSAID-associated cardiovascular thrombotic events and gastrointestinal bleeding/ulceration. Contraindicated in active peptic ulcers, CABG peri-operative period, severe heart failure, and severe renal/hepatic impairment.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or analgesic treatment guidance. Always consult a registered physician or orthopedic specialist before taking pain relievers, anti-inflammatory medications, or anti-arthritic therapies.
Aceclofenac 100mg + Paracetamol 325mg Tablets
Paracetamol / Acetaminophen (Tablets 500mg, 650mg, 1000mg; Oral Suspension 120mg, 125mg, 250mg per 5ml; Drops 100mg/ml) is a first-line non-opioid analgesic and antipyretic on the WHO Model List of Essential Medicines. It selectively inhibits central prostaglandin synthesis through peroxidase-dependent inhibition of COX enzymes in the brain and spinal cord, activates descending serotonergic inhibitory pathways, and resets the hypothalamic thermoregulatory center to reduce fever through cutaneous vasodilation and sweating. Unlike NSAIDs, it does NOT inhibit peripheral cyclooxygenase, causing zero gastric mucosal ulceration, platelet dysfunction, or renal vasoconstriction. Indicated as first-line therapy for mild-to-moderate pain (headache, toothache, dysmenorrhea, osteoarthritis) and fever of diverse etiologies.
Aceclofenac Tablets 100 mg
Aceclofenac Tablets (100mg, 200mg Sustained Release) is an oral phenylacetic acid-derivative non-steroidal anti-inflammatory drug (NSAID) on the WHO Model List framework. It exhibits preferential inhibition of the COX-2 isoenzyme over COX-1, dramatically reducing synthesis of pro-inflammatory cytokines (IL-1beta, TNF-alpha) and PGE2, while stimulating synthesis of extracellular cartilage matrix components (glycosaminoglycans) in articular cartilage. Indicated for symptomatic relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute musculoskeletal pain.
Aceclofenac 100mg + Paracetamol 325mg + Serratiopeptidase 15mg Tablets
Paracetamol / Acetaminophen (Tablets 500mg, 650mg, 1000mg; Oral Suspension 120mg, 125mg, 250mg per 5ml; Drops 100mg/ml) is a first-line non-opioid analgesic and antipyretic on the WHO Model List of Essential Medicines. It selectively inhibits central prostaglandin synthesis through peroxidase-dependent inhibition of COX enzymes in the brain and spinal cord, activates descending serotonergic inhibitory pathways, and resets the hypothalamic thermoregulatory center to reduce fever through cutaneous vasodilation and sweating. Unlike NSAIDs, it does NOT inhibit peripheral cyclooxygenase, causing zero gastric mucosal ulceration, platelet dysfunction, or renal vasoconstriction. Indicated as first-line therapy for mild-to-moderate pain (headache, toothache, dysmenorrhea, osteoarthritis) and fever of diverse etiologies.
Thiocolchicoside 4mg + Aceclofenac 100mg Tablets
Aceclofenac (100mg) and Thiocolchicoside (4mg/8mg, with or without Paracetamol 325mg) Tablets is a potent muscle relaxant and anti-inflammatory combination. Aceclofenac inhibits COX-2-mediated prostaglandin synthesis, reducing joint and tissue inflammation. Thiocolchicoside is a semi-synthetic sulfur derivative of colchicoside that acts as a competitive antagonist at GABA-A and glycine receptors, exerting central muscle relaxant action to eliminate painful muscle contractures without causing heavy sedative drowsiness. Indicated for acute painful musculoskeletal conditions, acute lumbago, cervical radiculopathy, sprains, spasms, and post-traumatic muscle contractures.