InjectionClinical Overview
Lignocaine (Lidocaine) Hydrochloride is the gold-standard amino-amide local anesthetic and Class Ib antiarrhythmic agent on the WHO Model List of Essential Medicines. It reversibly blocks voltage-gated sodium channels in neuronal cell membranes, stopping the generation and propagation of pain signals. When combined with Adrenaline (Epinephrine 1:80,000), localized vasoconstriction reduces surgical bleeding, slows systemic anesthetic absorption, and doubles the duration of local anesthesia. Indicated for infiltration anesthesia, regional nerve blocks, epidural anesthesia, and treatment of acute ventricular arrhythmias.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Administered by a licensed healthcare professional by local infiltration, nerve block, or IV infusion under sterile conditions. Always aspirate before injection to verify no vascular penetration. Lignocaine with Adrenaline must NEVER be injected into end-artery structures (fingers, toes, nose, ears, penis) due to risk of ischemic necrosis.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Local numbness, stinging at injection site, transient dizziness. Rare/Severe: Local Anesthetic Systemic Toxicity (LAST: perioral numbness, tinnitus, muscle twitching, seizures, cardiovascular collapse), anaphylaxis, and ischemic tissue necrosis with adrenaline.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Strictly avoid formulations with Adrenaline in end-artery appendages (digits, ears, nose, penis) due to gangrene risk. Toxic doses or accidental IV injection causes LAST; have lipid emulsion and resuscitation equipment ready. Caution in cardiac arrhythmias and severe liver disease.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Lignocaine + Adrenaline Injection (2%w/v + 1:80000)
Lignocaine (Lidocaine) Hydrochloride is the gold-standard amino-amide local anesthetic and Class Ib antiarrhythmic agent on the WHO Model List of Essential Medicines. It reversibly blocks voltage-gated sodium channels in neuronal cell membranes, stopping the generation and propagation of pain signals. When combined with Adrenaline (Epinephrine 1:80,000), localized vasoconstriction reduces surgical bleeding, slows systemic anesthetic absorption, and doubles the duration of local anesthesia. Indicated for infiltration anesthesia, regional nerve blocks, epidural anesthesia, and treatment of acute ventricular arrhythmias.
Lignocaine Hydrochloride Injection (20ml)
Lignocaine (Lidocaine) Hydrochloride is the gold-standard amino-amide local anesthetic and Class Ib antiarrhythmic agent on the WHO Model List of Essential Medicines. It reversibly blocks voltage-gated sodium channels in neuronal cell membranes, stopping the generation and propagation of pain signals. When combined with Adrenaline (Epinephrine 1:80,000), localized vasoconstriction reduces surgical bleeding, slows systemic anesthetic absorption, and doubles the duration of local anesthesia. Indicated for infiltration anesthesia, regional nerve blocks, epidural anesthesia, and treatment of acute ventricular arrhythmias.
Clotrimazole 1% w/v + Lignocaine Hydrochloride 2% w/v Ear Drops
Clotrimazole and Lignocaine Hydrochloride ear drops is an antifungal and local anesthetic otic combination. Clotrimazole (1% w/v) disrupts fungal cell membrane permeability, eradicating Aspergillus niger and Candida species responsible for otomycosis, while lignocaine (2% w/v) reversibly blocks neuronal sodium channels, providing rapid relief of severe deep ear pain and pruritus. Indicated for fungal otitis externa (otomycosis) accompanied by pain and inflammation.
Paradichlorobenzene (2% w/v) + Chlorbutol (5% w/v) + Turpentine Oil (15% w/v) + Lidocaine (2% w/v) Ear drop
Ceruminolytic Ear Drop formulation combining Paradichlorobenzene (2%), Chlorbutol (5%), Turpentine Oil (15%), and Lidocaine (2%). Paradichlorobenzene hydrates and dissolves hard impacted cerumen; turpentine oil acts as a counter-irritant and cerumen liquefier; chlorbutol provides mild antibacterial and antifungal preservation; and lidocaine relieves localized ear canal pain and tension. Indicated for softening, loosening, and removal of hardened, impacted ear wax.