DropsClinical Overview
Clotrimazole and Lignocaine Hydrochloride ear drops is an antifungal and local anesthetic otic combination. Clotrimazole (1% w/v) disrupts fungal cell membrane permeability, eradicating Aspergillus niger and Candida species responsible for otomycosis, while lignocaine (2% w/v) reversibly blocks neuronal sodium channels, providing rapid relief of severe deep ear pain and pruritus. Indicated for fungal otitis externa (otomycosis) accompanied by pain and inflammation.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Tilt head sideways with the affected ear facing upwards. Instill 3 to 4 drops into the ear canal. Maintain the head tilt for 3 to 5 minutes to allow penetration down the auditory canal. Repeat 3 to 4 times daily for 7 to 10 days. Keep the ear completely dry during bathing.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Mild localized burning, stinging, erythema in ear canal. Rare/Severe: Contact dermatitis.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in patients with a perforated tympanic membrane (eardrum perforation); do not use if ear drainage/discharge contains pus or blood until examined by an ENT specialist. Strictly for otic instillation; do not ingest or put in eyes.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or ophthalmic treatment recommendations. Always consult a registered ophthalmologist or ENT specialist before initiating, changing, or instilling any ophthalmic or otic medication.
Clotrimazole Cream 1%
Clotrimazole (1% w/w cream, lotion, or dusting powder) is a versatile broad-spectrum imidazole antifungal on the WHO Model List of Essential Medicines. It inhibits fungal cytochrome P450 14-alpha-demethylase, depleting ergosterol and increasing fungal cell permeability. Dusting powder formulation absorbs excess moisture in intertriginous skin folds, preventing fungal maceration. Indicated for tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis, and prevention of recurrence in sweaty body folds.
Beclomethasone Dipropionate 0.025%, Clotrimazole 1% and Gentamicin Sulphate 0.1% Cream
Clotrimazole (1% w/w cream, lotion, or dusting powder) is a versatile broad-spectrum imidazole antifungal on the WHO Model List of Essential Medicines. It inhibits fungal cytochrome P450 14-alpha-demethylase, depleting ergosterol and increasing fungal cell permeability. Dusting powder formulation absorbs excess moisture in intertriginous skin folds, preventing fungal maceration. Indicated for tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis, and prevention of recurrence in sweaty body folds.
Lignocaine Injection 2% w/v
Lignocaine (Lidocaine) Hydrochloride is the gold-standard amino-amide local anesthetic and Class Ib antiarrhythmic agent on the WHO Model List of Essential Medicines. It reversibly blocks voltage-gated sodium channels in neuronal cell membranes, stopping the generation and propagation of pain signals. When combined with Adrenaline (Epinephrine 1:80,000), localized vasoconstriction reduces surgical bleeding, slows systemic anesthetic absorption, and doubles the duration of local anesthesia. Indicated for infiltration anesthesia, regional nerve blocks, epidural anesthesia, and treatment of acute ventricular arrhythmias.
Lignocaine + Adrenaline Injection (2%w/v + 1:80000)
Lignocaine (Lidocaine) Hydrochloride is the gold-standard amino-amide local anesthetic and Class Ib antiarrhythmic agent on the WHO Model List of Essential Medicines. It reversibly blocks voltage-gated sodium channels in neuronal cell membranes, stopping the generation and propagation of pain signals. When combined with Adrenaline (Epinephrine 1:80,000), localized vasoconstriction reduces surgical bleeding, slows systemic anesthetic absorption, and doubles the duration of local anesthesia. Indicated for infiltration anesthesia, regional nerve blocks, epidural anesthesia, and treatment of acute ventricular arrhythmias.