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Official PMBI MRP is being updated for catalog code 2253.
Locate Jan Aushadhi KendraClinical Overview
Bisacodyl Suppositories (5mg, 10mg) is a rectal stimulant diphenylmethane laxative on the WHO Model List of Essential Medicines. Following rectal insertion, bisacodyl is hydrolyzed by endogenous esterases to active bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), directly stimulating sensory nerve endings in the colonic and rectal mucosa to initiate vigorous propulsive peristalsis within 15 to 60 minutes. Indicated for acute constipation, evacuation of the colon prior to surgical or radiological procedures, and bowel retraining in neurogenic bowel.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Administer rectally: Adults: 10 mg suppository; Children: 5 mg suppository. Remove the protective wrapper, moisten the tip with water or lubricant, and insert pointed end first into the rectum while lying on the side with knees bent. Retain for 15 to 30 minutes until the urge to defecate occurs.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Rectal burning, tenesmus, mild abdominal cramps. Rare/Severe: Proctitis, sloughing of rectal mucosa with chronic use, and electrolyte disturbances.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
For rectal use only. Not for continuous long-term daily use (can cause laxative dependence). Contraindicated in acute surgical abdomen, acute appendicitis, rectal bleeding, and anal fissures.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or gastrointestinal treatment recommendations. Always consult a registered gastroenterologist or qualified medical practitioner before initiating, altering, or discontinuing any gastrointestinal medication or digestive therapy.
Bisacodyl Tablets 5mg
Bisacodyl Tablets (5mg) is an oral stimulant laxative on the WHO Model List of Essential Medicines. It acts locally on the colonic mucosa after passage through the small bowel, stimulating enteric intramural plexuses to induce mass peristalsis and promote fluid and electrolyte accumulation in the lumen. Onset of action is 6 to 12 hours. Indicated for short-term relief of occasional constipation and bowel prep prior to colonoscopy or abdominal surgery.
Bisacodyl Suppositories 10mg
Bisacodyl Suppositories (5mg, 10mg) is a rectal stimulant diphenylmethane laxative on the WHO Model List of Essential Medicines. Following rectal insertion, bisacodyl is hydrolyzed by endogenous esterases to active bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), directly stimulating sensory nerve endings in the colonic and rectal mucosa to initiate vigorous propulsive peristalsis within 15 to 60 minutes. Indicated for acute constipation, evacuation of the colon prior to surgical or radiological procedures, and bowel retraining in neurogenic bowel.