Bisacodyl

Bisacodyl Tablets (5mg) is an oral stimulant laxative on the WHO Model List of Essential Medicines. It acts locally on the colonic mucosa after passage through the small bowel, stimulating enteric intramural plexuses to induce mass peristalsis and promote fluid and electrolyte accumulation in the lumen. Onset of action is 6 to 12 hours. Indicated for short-term relief of occasional constipation and bowel prep prior to colonoscopy or abdominal surgery.

Bisacodyl Suppositories (5mg, 10mg) is a rectal stimulant diphenylmethane laxative on the WHO Model List of Essential Medicines. Following rectal insertion, bisacodyl is hydrolyzed by endogenous esterases to active bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), directly stimulating sensory nerve endings in the colonic and rectal mucosa to initiate vigorous propulsive peristalsis within 15 to 60 minutes. Indicated for acute constipation, evacuation of the colon prior to surgical or radiological procedures, and bowel retraining in neurogenic bowel.

Bisacodyl Suppositories (5mg, 10mg) is a rectal stimulant diphenylmethane laxative on the WHO Model List of Essential Medicines. Following rectal insertion, bisacodyl is hydrolyzed by endogenous esterases to active bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), directly stimulating sensory nerve endings in the colonic and rectal mucosa to initiate vigorous propulsive peristalsis within 15 to 60 minutes. Indicated for acute constipation, evacuation of the colon prior to surgical or radiological procedures, and bowel retraining in neurogenic bowel.