InjectionClinical Overview
Ketorolac Tromethamine Injection (30mg/ml) is a parenteral pyrrolo-pyrrole NSAID on the WHO Model List of Essential Medicines. It provides powerful non-opioid analgesia comparable to therapeutic doses of morphine by potently inhibiting COX-1 and COX-2 without causing respiratory depression, sedation, or bowel hypomotility. Indicated for short-term management (up to 5 days only) of moderate-to-severe acute postoperative surgical pain.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Administer by slow intravenous injection (over at least 15 seconds) or deep intramuscular injection: 30 mg every 6 hours as needed (15 mg every 6 hours in elderly >65 years, patients <50 kg, or moderate renal impairment). Maximum daily dose is 120 mg (60 mg in elderly/renal impairment). MAXIMUM COMBINED DURATION IS STRICTLY 5 DAYS.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Nausea, dyspepsia, headache, injection site pain, drowsiness, dizziness. Rare/Severe: Severe gastrointestinal hemorrhage and perforation, acute renal failure, postoperative operative site bleeding, and anaphylactoid shock.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black Box Warning: High risk of fatal gastrointestinal bleeding, ulceration, and perforation; Black Box Warning: Renal failure; Black Box Warning: Increased bleeding risk; Black Box Warning: MAXIMUM DURATION OF THERAPY (IV + oral combined) IS STRICTLY 5 DAYS. Strictly contraindicated in active peptic ulcer, labor and delivery, CABG surgery, suspected cerebrovascular bleeding, and advanced renal impairment.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or analgesic treatment guidance. Always consult a registered physician or orthopedic specialist before taking pain relievers, anti-inflammatory medications, or anti-arthritic therapies.
Ketorolac Tromethamine Tablets 10mg
Ketorolac Tromethamine Tablets / Dispersible Tablets (10mg) is an oral pyrrolizine carboxylic acid NSAID on the WHO Model List framework for short-term continuation therapy following IV ketorolac. It exerts potent analgesic and moderate anti-inflammatory action via cyclooxygenase inhibition. Indicated ONLY as continuation therapy to parenteral ketorolac for moderate-to-severe acute postoperative pain, for a total combined duration not exceeding 5 days.
Ketorolac Tromethamine Dispersible Tablet 10 mg
Ketorolac Tromethamine Tablets / Dispersible Tablets (10mg) is an oral pyrrolizine carboxylic acid NSAID on the WHO Model List framework for short-term continuation therapy following IV ketorolac. It exerts potent analgesic and moderate anti-inflammatory action via cyclooxygenase inhibition. Indicated ONLY as continuation therapy to parenteral ketorolac for moderate-to-severe acute postoperative pain, for a total combined duration not exceeding 5 days.
Ketorolac Tromethamine Ophthalmic Solution 0.4% w/v
Ketorolac Tromethamine Ophthalmic Solution (0.4% w/v) is a topical ocular NSAID on the WHO Model List framework. It inhibits ocular cyclooxygenase to block ocular prostaglandin synthesis, preventing intraoperative miosis and relieving postoperative ocular inflammation and photophobia following cataract surgery and refractive surgery.
Ketorolac (0.5% W/V) + Moxifloxacin (0.5% W/V) Eye Drops
Moxifloxacin and NSAID (Bromfenac 0.09% or Ketorolac 0.5%) ophthalmic solution is an antibacterial and non-steroidal anti-inflammatory combination. Moxifloxacin provides broad bactericidal coverage, while the ophthalmic NSAID inhibits cyclooxygenase (COX-1/COX-2) enzymes to block prostaglandin synthesis, relieving ocular pain, photophobia, and anterior chamber flare without the intraocular pressure spikes or cataract risks associated with steroids. Indicated for post-cataract surgery ocular pain, inflammation, and infection prophylaxis.