CapsulesClinical Overview
Statin and Antiplatelet (Aspirin +/- Clopidogrel) cardiovascular polypill formulation. Unites intensive lipid lowering and plaque stabilization (via HMG-CoA reductase inhibition) with antiplatelet thrombus prevention (via irreversible COX-1 inhibition and/or ADP P2Y12 platelet receptor blockade). Indicated for secondary prevention in coronary artery disease, acute coronary syndrome, post-percutaneous coronary intervention (PCI/stenting), and ischemic stroke.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once daily with or immediately after a substantial meal with a full glass of water. Swallow gastro-resistant capsules/tablets whole. Bedtime or evening administration is optimal.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Dyspepsia, heartburn, nausea, minor bruising, epistaxis, muscle ache. Rare/Severe: Major gastrointestinal bleeding, intracranial hemorrhage, rhabdomyolysis, and severe thrombocytopenia.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Increased risk of gastrointestinal ulceration and bleeding; report dark tarry stools or vomiting blood immediately. Contraindicated in active peptic ulceration, bleeding diathesis, severe hepatic impairment, and pregnancy. Discontinue 5-7 days before scheduled major elective surgery if advised by cardiologist.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified cardiologist/pharmacist before initiating, altering, or substituting any cardiovascular medication.
Aspirin Gastro-resistant Tablets 150 mg
Aspirin Gastro-Resistant Tablets (150mg) is an acetylated salicylate on the WHO Model List of Essential Medicines. It irreversibly acetylates the serine 529 residue of cyclooxygenase-1 (COX-1), permanently suppressing platelet thromboxane A2 (TXA2) generation for the entire lifespan of the platelet (7-10 days). Enteric coating bypasses the stomach to dissolve in the alkaline duodenum, minimizing direct contact gastric mucosal injury. Indicated for secondary prevention of myocardial infarction, ischemic stroke, transient ischemic attacks (TIA), and unstable angina.
Atorvastatin Tablets 10mg
HMG-CoA Reductase Inhibitor (Statin) on the WHO Model List of Essential Medicines. It competitively inhibits 3-hydroxy-3-methylglutaryl-coenzyme A reductase, the rate-limiting enzyme in cholesterol biosynthesis, upregulating hepatic LDL receptors and drastically clearing circulating atherogenic LDL-C, VLDL, and triglycerides while increasing HDL-C and stabilizing atherosclerotic plaques. Indicated for primary hypercholesterolemia, mixed dyslipidemia, and primary/secondary prevention of cardiovascular events (myocardial infarction, stroke, revascularization).
Atorvastatin Tablets 20mg
HMG-CoA Reductase Inhibitor (Statin) on the WHO Model List of Essential Medicines. It competitively inhibits 3-hydroxy-3-methylglutaryl-coenzyme A reductase, the rate-limiting enzyme in cholesterol biosynthesis, upregulating hepatic LDL receptors and drastically clearing circulating atherogenic LDL-C, VLDL, and triglycerides while increasing HDL-C and stabilizing atherosclerotic plaques. Indicated for primary hypercholesterolemia, mixed dyslipidemia, and primary/secondary prevention of cardiovascular events (myocardial infarction, stroke, revascularization).
Clopidogrel 75mg + Aspirin 75mg Tablets
Clopidogrel and Aspirin is the cornerstone Dual Antiplatelet Therapy (DAPT) on the WHO Model List of Essential Medicines. Aspirin irreversibly acetylates platelet cyclooxygenase-1 (COX-1), blocking thromboxane A2 production, while clopidogrel is an oral thienopyridine prodrug whose active metabolite irreversibly binds to platelet P2Y12 adenosine diphosphate (ADP) receptors, preventing ADP-mediated glycoprotein IIb/IIIa activation. This dual blockade potently inhibits platelet aggregation across complementary pathways. Indicated for acute coronary syndromes (STEMI, NSTEMI, unstable angina) and prevention of subacute stent thrombosis following percutaneous coronary intervention (PCI).