Clinical Overview
Etodolac Tablets (300mg) is an oral pyranocarboxylic acid NSAID with preferential COX-2 selectivity on the WHO Model List framework. It selectively inhibits COX-2 over COX-1, providing effective articular anti-inflammatory action with lower incidence of gastroduodenal mucosal injury compared to non-selective agents. Indicated for acute and long-term management of signs and symptoms of osteoarthritis and rheumatoid arthritis, and acute mild-to-moderate pain.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally 300 mg to 400 mg two to three times daily, or 600 mg to 1000 mg once daily with food and water. Swallow whole.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Dyspepsia, nausea, abdominal pain, diarrhea, dizziness, headache. Rare/Severe: Peptic ulceration, gastrointestinal hemorrhage, cardiovascular thrombotic events, and fluid retention.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black Box Warning: Cardiovascular thrombotic events and gastrointestinal bleeding. Contraindicated in active peptic ulcer disease, CABG surgery, and third-trimester pregnancy.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or analgesic treatment guidance. Always consult a registered physician or orthopedic specialist before taking pain relievers, anti-inflammatory medications, or anti-arthritic therapies.