InjectionClinical Overview
Artesunate is a water-soluble hemisuccinate derivative of artemisinin and the WHO gold-standard first-line treatment for severe malaria. Its endoperoxide bridge is cleaved by intraparasitic heme-iron, generating free radicals that alkylate essential parasitic proteins and PfATP6, rapidly reducing parasite biomass within hours. Indicated parenterally for severe Plasmodium falciparum and vivax malaria, cerebral malaria, and complicated malarial infections.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Administered strictly by a qualified healthcare professional by slow intravenous injection over 1-2 minutes or deep intramuscular injection after reconstitution with sodium bicarbonate diluent and 5% Dextrose/Normal Saline. Full parenteral course followed by oral ACT as soon as patient can tolerate oral medications.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Dizziness, nausea, vomiting, mild abdominal pain, headache, transient reticulocytopenia. Rare/Severe: Delayed post-artesunate hemolytic anemia (occurring 1-3 weeks after treatment), severe hypersensitivity/anaphylaxis, and cardiotoxicity at excessive doses.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Monitor hemoglobin and hematocrit for up to 4 weeks following treatment to detect delayed post-artesunate hemolysis. Once the patient is stabilized and capable of oral intake, a complete 3-day course of an alternative oral ACT must be completed to prevent recrudescence.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Artesunate Injection 120mg
Artesunate is a water-soluble hemisuccinate derivative of artemisinin and the WHO gold-standard first-line treatment for severe malaria. Its endoperoxide bridge is cleaved by intraparasitic heme-iron, generating free radicals that alkylate essential parasitic proteins and PfATP6, rapidly reducing parasite biomass within hours. Indicated parenterally for severe Plasmodium falciparum and vivax malaria, cerebral malaria, and complicated malarial infections.
Artesunate 200mg Tablets + Sulfadoxine 500mg + Pyrimethamine 25mg Tablets Combi kit
Artesunate, Sulfadoxine, and Pyrimethamine Combi Kit is a WHO-endorsed Artemisinin-based Combination Therapy (ACT). Artesunate acts rapidly to clear the bulk of malaria parasites by releasing reactive carbon-centered free radicals, while sulfadoxine (dihydropteroate synthase inhibitor) and pyrimethamine (dihydrofolate reductase inhibitor) provide synergistic long-acting anti-folate elimination of residual parasites. Indicated for the treatment of acute uncomplicated Plasmodium falciparum malaria.