CreamClinical Overview
Lignocaine (Lidocaine) and Nifedipine topical cream is a specialized anorectal formulation. Lignocaine reversibly blocks neuronal sodium channels to provide rapid local analgesia, relieving severe anal pain and spasm, while nifedipine, a calcium channel blocker, relaxes the hypertonic internal anal sphincter muscle, reducing resting anal pressure and enhancing local mucosal blood perfusion to promote tissue healing. Indicated for the conservative medical management of acute and chronic anal fissures.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
For topical anorectal application only. Wash hands thoroughly. Apply a small pea-sized amount to the anal verge and gently inside the anal opening twice daily (morning and bedtime) and after bowel movements, using an applicator or clean finger. Use for 4 to 6 weeks as prescribed.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Local burning, mild stinging, pruritus. Rare/Severe: Systemic absorption effects (mild headache, dizziness, postural hypotension).
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
For external/anorectal use only. Avoid contact with eyes. Discontinue if rectal bleeding increases or severe allergic dermatitis occurs. Wash hands thoroughly after application.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
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