TabletsMRP Under Process
Official PMBI MRP is being updated for catalog code 2560.
Locate Jan Aushadhi KendraClinical Overview
Frusemide (40mg) and Potassium Chloride Controlled Release (600mg CR) Tablets combines a high-ceiling loop diuretic with a potassium replenishment core. Frusemide induces significant renal loss of potassium and chloride alongside sodium and water; the controlled-release potassium chloride wax-matrix core dissolves gradually along the small intestine, replenishing potassium losses and preventing diuretic-induced hypokalemic metabolic alkalosis, muscle weakness, and cardiac dysrhythmias. Indicated for fluid overload in heart failure, nephrotic syndrome, and hepatic edema.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally 1 tablet once daily in the morning with a meal and a full glass of water. Swallow whole; do NOT chew or crush the tablet to prevent mucosal potassium ulceration. Remain upright for at least 30 minutes.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Increased urination, nausea, epigastric discomfort, abdominal cramps. Rare/Severe: Gastrointestinal ulceration or stenosis from localized potassium chloride, severe hypokalemia or hyperkalemia, and dehydration.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in severe renal impairment, hyperkalemia, and esophageal or gastrointestinal strictures. Swallow whole with plenty of fluids to prevent tablet lodge in esophagus.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, nephrological diagnosis, or urological treatment recommendations. Always consult a registered nephrologist, urologist, or qualified medical practitioner before initiating, modifying, or discontinuing any kidney or urinary tract medication.
Frusemide Injection 10 mg per ml
Frusemide Injection 10 mg per ml is an evidence-based cardiovascular and hemodynamic pharmaceutical formulation. It acts by modulating vascular smooth muscle tone, autonomic receptors, or fluid-electrolyte balance to manage cardiovascular disease.
Frusemide Tablets 40 mg
Frusemide Tablets 40 mg is an evidence-based cardiovascular and hemodynamic pharmaceutical formulation. It acts by modulating vascular smooth muscle tone, autonomic receptors, or fluid-electrolyte balance to manage cardiovascular disease.
Ringer Lactate Infusion
Ringer's Lactate IV Infusion (Hartmann's Solution 500ml) is a sterile, balanced, isotonic crystalloid solution on the WHO Model List of Essential Medicines containing sodium chloride, potassium chloride, calcium chloride, and sodium lactate in physiological concentrations approximating human extracellular fluid (osmolarity ~273 mOsm/L). Lactate ions are metabolized in the liver via gluconeogenesis and the citric acid cycle into bicarbonate ions, gently buffering metabolic acidosis without the hyperchloremic metabolic acidosis associated with normal saline. Indicated for replacement of extracellular fluid and electrolyte losses in acute hypovolemic shock, major burns, acute hemorrhage, intraoperative fluid maintenance, and surgical dehydration.
Frusemide 20mg + Spironolactone 50mg Tablets
Spironolactone is a synthetic steroid competitive mineralocorticoid receptor (aldosterone) antagonist and potassium-sparing diuretic on the WHO Model List of Essential Medicines. It blocks aldosterone binding in the late distal renal tubules and cortical collecting ducts, increasing sodium and water excretion while conserving potassium and hydrogen ions. In heart failure, it blocks aldosterone-mediated myocardial fibrosis and endothelial dysfunction. Indicated for heart failure with reduced ejection fraction (NYHA class II-IV), primary hyperaldosteronism, cirrhosis with ascites, resistant hypertension, and nephrotic edema.