MRP Under Process
Official PMBI MRP is being updated for catalog code 2559.
Locate Jan Aushadhi KendraClinical Overview
Frusemide (40mg) and Amiloride (5mg) Tablets is a balanced loop and potassium-retaining diuretic combination on the WHO Model List of Essential Medicines. Frusemide exerts potent, rapid natriuresis in the loop of Henle, while amiloride blocks luminal epithelial sodium channels (ENaC) in the cortical collecting tubule, blunting potassium excretion without antiandrogenic hormonal effects. Indicated for congestive heart failure edema, hepatic cirrhosis with ascites, and nephrotic edema in patients prone to hypokalemia.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally 1 tablet once daily in the morning with breakfast with a glass of water. Swallow whole.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Polyuria, dizziness, headache, mild nausea, muscle cramps. Rare/Severe: Hyperkalemia (if taken with potassium or in renal failure), severe dehydration, and hypotension.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Strictly contraindicated in hyperkalemia, acute anuric renal failure, and pre-existing severe renal impairment. Avoid concomitant potassium supplements or potassium-sparing agents.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, nephrological diagnosis, or urological treatment recommendations. Always consult a registered nephrologist, urologist, or qualified medical practitioner before initiating, modifying, or discontinuing any kidney or urinary tract medication.