Amiloride

Amiloride 2.5mg + Hydrochlorothiazide 25mg Tablet is an evidence-based cardiovascular and hemodynamic pharmaceutical formulation. It acts by modulating vascular smooth muscle tone, autonomic receptors, or fluid-electrolyte balance to manage cardiovascular disease.

Frusemide (40mg) and Amiloride (5mg) Tablets is a balanced loop and potassium-retaining diuretic combination on the WHO Model List of Essential Medicines. Frusemide exerts potent, rapid natriuresis in the loop of Henle, while amiloride blocks luminal epithelial sodium channels (ENaC) in the cortical collecting tubule, blunting potassium excretion without antiandrogenic hormonal effects. Indicated for congestive heart failure edema, hepatic cirrhosis with ascites, and nephrotic edema in patients prone to hypokalemia.

Torasemide (10mg) and Amiloride (5mg) Tablets is a fixed-dose loop and potassium-sparing diuretic combination. Torasemide blocks the Na+/K+/2Cl- cotransporter in the loop of Henle, while amiloride selectively blocks epithelial sodium channels (ENaC) in the late distal tubule and cortical collecting duct, preventing potassium loss driven by torasemide's high distal tubular sodium delivery. Indicated for refractory edema associated with congestive heart failure, nephrotic syndrome, and hepatic cirrhosis.