TabletsClinical Overview
Sumatriptan (85mg) and Naproxen Sodium (500mg) Tablets is a fixed-dose acute antimigraine therapy. Sumatriptan is a selective 5-HT1B/1D serotonin receptor agonist that constricts painfully dilated intracranial extracerebral blood vessels and inhibits pro-inflammatory neuropeptide release from trigeminal nerve terminals. Naproxen provides long-acting COX inhibition to suppress neurogenic dural inflammation and prevent headache recurrence. Indicated for acute treatment of migraine attacks with or without aura in adults.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally 1 tablet with water at the earliest onset of migraine headache. If headache returns or patient has partial response, a second tablet may be taken after at least 2 hours (maximum 2 tablets in 24 hours). Swallow whole.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Chest tightness/pressure (triptan chest sensations), dizziness, somnolence, paresthesias, nausea, dyspepsia, dry mouth. Rare/Severe: Coronary artery vasospasm, myocardial infarction, stroke, arrhythmias, and GI ulceration.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in coronary artery disease, history of myocardial infarction, Prinzmetal angina, uncontrolled hypertension, peripheral vascular disease, and stroke. Do not use within 24 hours of ergotamines or other triptans.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or analgesic treatment guidance. Always consult a registered physician or orthopedic specialist before taking pain relievers, anti-inflammatory medications, or anti-arthritic therapies.
Naproxen Tablets 500 mg
Naproxen Tablets (250mg, 500mg) is an oral propionic acid NSAID on the WHO Model List of Essential Medicines. It reversibly inhibits both COX-1 and COX-2 enzymes, suppressing prostaglandin synthesis. Due to its long elimination half-life (12 to 17 hours), it provides sustained 24-hour platelet inhibition, conferring the most favorable cardiovascular safety profile among all traditional NSAIDs. Indicated for relief of pain and inflammation in rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, acute tendinitis, bursitis, and primary dysmenorrhea.
Naproxen Tablets 250 mg
Naproxen Tablets (250mg, 500mg) is an oral propionic acid NSAID on the WHO Model List of Essential Medicines. It reversibly inhibits both COX-1 and COX-2 enzymes, suppressing prostaglandin synthesis. Due to its long elimination half-life (12 to 17 hours), it provides sustained 24-hour platelet inhibition, conferring the most favorable cardiovascular safety profile among all traditional NSAIDs. Indicated for relief of pain and inflammation in rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, acute tendinitis, bursitis, and primary dysmenorrhea.
Naproxen 250 mg + Domperidone 10 mg Tablet
Naproxen (250mg/500mg) and Domperidone (10mg) Tablets is a migraine and arthritic combination. Naproxen eliminates pain and neurogenic inflammation; domperidone accelerates gastric emptying through peripheral dopamine D2 antagonism, reversing migraine-induced gastric stasis and relieving migraine nausea. Indicated for acute migraine attacks and arthritic pain with gastric fullness.
Naproxen 500 mg + Domperidone 10 mg Tablet
Naproxen (250mg/500mg) and Domperidone (10mg) Tablets is a migraine and arthritic combination. Naproxen eliminates pain and neurogenic inflammation; domperidone accelerates gastric emptying through peripheral dopamine D2 antagonism, reversing migraine-induced gastric stasis and relieving migraine nausea. Indicated for acute migraine attacks and arthritic pain with gastric fullness.