CapsulesClinical Overview
Ribavirin Capsules (200mg) is a synthetic guanosine nucleoside analogue antiviral on the WHO Model List of Essential Medicines. It inhibits inosine monophosphate dehydrogenase (IMPDH), depleting intracellular GTP pools and accelerating viral mutagenesis. Indicated in combination with direct-acting antivirals (e.g. sofosbuvir) for chronic hepatitis C in patients with decompensated cirrhosis or prior treatment failure.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally in two divided doses daily with food (morning and evening). Weight-based dosing: 1000 mg/day (<75 kg) or 1200 mg/day (>=75 kg). Swallow whole with water.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Hemolytic anemia, fatigue, nausea, insomnia, pruritus, dyspnea. Rare/Severe: Severe hemolytic anemia causing myocardial infarction or worsening coronary artery disease; teratogenic/embryocidal effects.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black Box Warning: Hemolytic anemia occurs in up to 10% of patients; monitor hemoglobin at baseline, week 2, and week 4. Black Box Warning: Extreme teratogenicity; contraindicated in pregnancy and in male partners of pregnant women. Strict dual contraception required during therapy and for 6 months post-treatment.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or gastrointestinal treatment recommendations. Always consult a registered gastroenterologist or qualified medical practitioner before initiating, altering, or discontinuing any gastrointestinal medication or digestive therapy.