TabletsClinical Overview
Silymarin Tablets (140mg) is a purified extract of flavonolignans (primarily silybin) from milk thistle (Silybum marianum) on the PMBI formulary. It acts as a potent antioxidant, scavenges reactive oxygen species, prevents lipid peroxidation of cell membranes, stimulates nucleolar polymerase A to enhance ribosomal protein synthesis, and exerts antifibrotic effects by suppressing hepatic stellate cell activation. Indicated as supportive therapy in chronic inflammatory liver disease, non-alcoholic fatty liver disease (NAFLD), and toxin/alcohol-induced liver injury.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally 140 mg two to three times daily after meals with a glass of water. Swallow whole. Recommended duration: 4 to 12 weeks.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Mild laxative effect, bloating, nausea, dyspepsia. Extremely safe and well tolerated.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Over-The-Counter supportive liver therapeutic. Not a substitute for avoiding hepatotoxic agents (alcohol). Caution in patients with known allergy to Asteraceae family plants (ragweed, marigolds).
Over-The-Counter (OTC)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or gastrointestinal treatment recommendations. Always consult a registered gastroenterologist or qualified medical practitioner before initiating, altering, or discontinuing any gastrointestinal medication or digestive therapy.