TabletsClinical Overview
Alprazolam and Propranolol Hydrochloride is a synergistic psychotropic-cardiovascular formulation combining a triazolobenzodiazepine with a non-selective beta-adrenergic blocker. Alprazolam enhances central inhibitory GABAergic neurotransmission at the GABAA receptor, relieving psychological panic and tension, while propranolol competitively antagonizes peripheral beta-1 and beta-2 adrenergic receptors, curbing somatic autonomic manifestations of anxiety (palpitations, resting tachycardia, tremors, sweating). Indicated for situational anxiety, panic disorder with severe autonomic hyperactivity, and performance anxiety.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally with a glass of water, with or without meals. Use strictly as prescribed on a short-term basis. Do not abruptly discontinue because abrupt withdrawal can cause rebound anxiety, tremors, tachycardia, and seizures.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Somnolence, lightheadedness, bradycardia, hypotension, fatigue, dry mouth, cold extremities. Rare/Severe: Severe respiratory depression, bronchospasm in asthmatics, physical dependence, paradoxical excitement, and heart block.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in bronchial asthma, sinus bradycardia, second- or third-degree AV block, and cardiogenic shock. Boxed warning for benzodiazepine addiction, abuse, and misuse. Never consume alcohol while taking this medicine.
Schedule H1 (Prescription Required - Habit Forming Warning)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Alprazolam Tablets 0.25 mg
Alprazolam is a short-acting, high-potency triazolobenzodiazepine. It enhances the binding affinity of the major inhibitory neurotransmitter GABA to GABAA receptors, opening neuronal chloride ion channels, hyperpolarizing membranes, and producing rapid anxiolytic, sedative, muscle-relaxant, and anticonvulsant effects. Indicated for acute management of generalized anxiety disorder (GAD) and panic disorder with or without agoraphobia.
Alprazolam Tablets 0.5 mg
Alprazolam is a short-acting, high-potency triazolobenzodiazepine. It enhances the binding affinity of the major inhibitory neurotransmitter GABA to GABAA receptors, opening neuronal chloride ion channels, hyperpolarizing membranes, and producing rapid anxiolytic, sedative, muscle-relaxant, and anticonvulsant effects. Indicated for acute management of generalized anxiety disorder (GAD) and panic disorder with or without agoraphobia.
Propranolol Tablets 40 mg
Beta-adrenergic receptor antagonist (cardioselective beta-1 blocker, non-selective beta blocker, or third-generation vasodilating beta-blocker with alpha-blockade or nitric oxide release) on the WHO Model List of Essential Medicines. It competitively blocks adrenergic stimulation, reducing heart rate, myocardial contractility, cardiac output, and renin release. Indicated for hypertension, stable angina pectoris, heart failure, cardiac arrhythmias, and post-myocardial infarction secondary prevention.
Alprazolam 0.25mg + Fluoxetine 20mg Tablets
Alprazolam and Fluoxetine combines a fast-acting triazolobenzodiazepine with a selective serotonin reuptake inhibitor (SSRI). Alprazolam rapidly relieves acute psychic anxiety, insomnia, and agitation within hours, while fluoxetine provides sustained long-term modulation of central serotonergic pathways to treat underlying depressive and panic pathology over weeks. Indicated for major depressive disorder with comorbid anxiety or agitation.