Clinical Overview
Alprazolam and Fluoxetine combines a fast-acting triazolobenzodiazepine with a selective serotonin reuptake inhibitor (SSRI). Alprazolam rapidly relieves acute psychic anxiety, insomnia, and agitation within hours, while fluoxetine provides sustained long-term modulation of central serotonergic pathways to treat underlying depressive and panic pathology over weeks. Indicated for major depressive disorder with comorbid anxiety or agitation.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once daily in the morning with water, with or without food. Morning dosing prevents sleep disruption from fluoxetine. Discontinue gradually under clinical supervision.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Somnolence, nausea, insomnia, headache, anorexia, sexual dysfunction, dry mouth. Rare/Severe: Serotonin syndrome, suicidal thoughts in young patients, hyponatremia/SIADH, and dependence liability.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Boxed warnings for suicidality in adolescents and benzodiazepine dependence. Contraindicated with MAO inhibitors or pimozide. Avoid alcohol.
Schedule H1 (Prescription Required - Habit Forming Warning)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Alprazolam Tablets 0.25 mg
Alprazolam is a short-acting, high-potency triazolobenzodiazepine. It enhances the binding affinity of the major inhibitory neurotransmitter GABA to GABAA receptors, opening neuronal chloride ion channels, hyperpolarizing membranes, and producing rapid anxiolytic, sedative, muscle-relaxant, and anticonvulsant effects. Indicated for acute management of generalized anxiety disorder (GAD) and panic disorder with or without agoraphobia.
Alprazolam Tablets 0.5 mg
Alprazolam is a short-acting, high-potency triazolobenzodiazepine. It enhances the binding affinity of the major inhibitory neurotransmitter GABA to GABAA receptors, opening neuronal chloride ion channels, hyperpolarizing membranes, and producing rapid anxiolytic, sedative, muscle-relaxant, and anticonvulsant effects. Indicated for acute management of generalized anxiety disorder (GAD) and panic disorder with or without agoraphobia.
Fluoxetine Hydrochloride Capsules 20mg
Fluoxetine Hydrochloride is a prototype selective serotonin reuptake inhibitor (SSRI) on the WHO Model List of Essential Medicines. It blocks the presynaptic serotonin transporter (SERT) and possesses a long elimination half-life (1-3 days for parent drug, 7-15 days for active norfluoxetine), providing a built-in buffer against abrupt discontinuation syndrome. Also displays mild 5-HT2C antagonism, contributing to energizing/activating effects. Indicated for major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa, and panic disorder.
Alprazolam 0.25mg + Propranolol Hydrochloride 20mg Tablets
Alprazolam and Propranolol Hydrochloride is a synergistic psychotropic-cardiovascular formulation combining a triazolobenzodiazepine with a non-selective beta-adrenergic blocker. Alprazolam enhances central inhibitory GABAergic neurotransmission at the GABAA receptor, relieving psychological panic and tension, while propranolol competitively antagonizes peripheral beta-1 and beta-2 adrenergic receptors, curbing somatic autonomic manifestations of anxiety (palpitations, resting tachycardia, tremors, sweating). Indicated for situational anxiety, panic disorder with severe autonomic hyperactivity, and performance anxiety.