PowderClinical Overview
Saccharomyces Boulardii (250mg Capsules and Powder Sachets) is a non-pathogenic, tropical probiotic yeast on the WHO Model List framework. It thrives at human body temperature (37°C) and is naturally resistant to antibacterial antibiotics. In the gut lumen, it neutralizes bacterial toxins (Clostridioides difficile toxin A and B, cholera toxin), stimulates mucosal secretory IgA and brush border disaccharidases, and prevents pathogen translocation. Indicated for prevention and treatment of antibiotic-associated diarrhea, C. difficile recurrence, acute infectious rotaviral diarrhea, and enteral nutrition-related diarrhea.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Adults: Take 250 mg to 500 mg orally once or twice daily. Capsules: Swallow whole with water. Sachets: Empty contents into a glass of cool or room temperature water, milk, or juice and drink immediately. Do NOT mix with very hot (>50°C) or frozen liquids or alcohol, which kill the living yeast cells. Can be taken simultaneously with antibacterial antibiotics.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Mild flatulence, constipation. Rare/Severe: Fungemia and sepsis reported in patients with central venous lines, critically ill ICU patients, or severe immunosuppression.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Over-The-Counter probiotic yeast. Contraindicated in patients with central venous catheters or severe immunodeficiency due to fatal fungemia risk. Do not co-administer with oral antifungal medications (fluconazole, itraconazole), which inactivate S. boulardii.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or gastrointestinal treatment recommendations. Always consult a registered gastroenterologist or qualified medical practitioner before initiating, altering, or discontinuing any gastrointestinal medication or digestive therapy.
