PowderClinical Overview
Calcium Polystyrene Sulphonate Powder (15g sachet) is a cation-exchange resin on the WHO Model List framework for hyperkalemia. In the gastrointestinal tract (predominantly the colon), it releases calcium ions in exchange for potassium ions, binding potassium which is excreted in the feces. Indicated for treatment of hyperkalemia associated with acute and chronic kidney disease.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Oral: Suspend 15 g in 30 to 50 mL of water or syrup (never fruit juice containing potassium) and take 3 to 4 times daily. Rectal enema: Suspend 30 g in 100 to 200 mL of methylcellulose or water and retain in colon for at least 9 hours.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Nausea, constipation, fecal impaction, hypercalcemia, hypokalemia. Rare/Severe: Intestinal necrosis / bowel perforation (especially if mixed with sorbitol).
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Do NOT mix with sorbitol (risk of fatal intestinal necrosis). Monitor serum potassium and calcium frequently. Onset is slow (several hours); not for emergency immediate cardioprotection in severe hyperkalemia.
Prescription Medical Consumable
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Nutritional & Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice or clinical dietetic guidance. Dietary supplements, micronutrients, parenteral electrolytes, and specialized clinical nutrition should be used under the supervision of a registered medical practitioner or clinical nutritionist.
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