TabletsClinical Overview
Flupentixol and Melitracen is a classic psychoanaleptic fixed-dose combination. Flupentixol, a thioxanthene derivative, acts at low doses (0.5 mg) preferentially on presynaptic dopamine autoreceptors to increase dopaminergic tone and relieve apathy and anxiety, while melitracen, a bipolar tricyclic antidepressant, inhibits norepinephrine and serotonin reuptake. Together, they provide activating, anxiolytic, and mood-lifting action without causing marked sedation. Indicated for psychogenic depression, depressive neuroses, masked depression, and psychosomatic disorders accompanied by anxiety and apathy.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally twice daily, in the morning and midday with water, with or without food. Avoid evening dosing to prevent sleep disturbance. Complete the prescribed course.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Insomnia, restlessness, dry mouth, dizziness, tremor, blurred vision, fatigue. Rare/Severe: Tardive dyskinesia, cardiac arrhythmias, seizures, and neuroleptic malignant syndrome.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated during acute recovery from myocardial infarction, heart block, and concurrent MAOIs (requires 14-day washout). Not recommended in severely agitated or excitable patients. Avoid alcohol.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Flupentixol Tablets 0.5 mg
Flupentixol is a thioxanthene typical antipsychotic. At low doses (1-3 mg/day), it blocks presynaptic dopamine autoreceptors, stimulating dopamine turnover and exerting disinhibiting, mood-elevating, and anxiolytic effects; at higher doses, it blocks postsynaptic D2 receptors to control hallucinations and delusions. Indicated for maintenance treatment of schizophrenia, paranoid psychoses, and low-dose management of chronic depression with apathy.
Flupentixole 0.5mg + Nortriptyline 10mg Tablets
Nortriptyline Hydrochloride is a secondary amine tricyclic antidepressant and the active demethylated metabolite of amitriptyline. It selectively inhibits the reuptake of norepinephrine over serotonin, offering effective antidepressant and neuropathic analgesia with significantly less sedation, anticholinergic burden, and orthostatic hypotension than amitriptyline. Indicated for major depressive disorder and chronic neuropathic pain syndromes.