TabletsClinical Overview
Acebrophylline Capsules / Tablets (100mg, 200mg Sustained Release; alone or with Montelukast 10mg or Acetylcysteine 600mg) is a fixed salt of ambroxol and theophylline-7-acetic acid on the PMBI formulary. It exerts a triple therapeutic action: potent bronchodilation via phosphodiesterase inhibition; mucoregulatory and surfactant-stimulating action via ambroxol (stimulating alveolar type II pneumocytes to produce pulmonary surfactant, reducing mucus viscosity and improving mucociliary clearance); and anti-inflammatory inhibition of phospholipase A2 and leukotriene C4. Indicated for bronchial asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, and chronic spastic bronchitis with thick viscid sputum.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally 100 mg twice daily, or 200 mg sustained-release tablet once daily after meals with a full glass of water. Swallow whole.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Epigastric discomfort, nausea, diarrhea, heartburn, drowsiness, headache. Rare/Severe: Tachycardia, hypotension, and transaminase elevations.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in acute myocardial infarction, severe hypotension, active peptic ulcer disease, and severe renal/hepatic impairment. Take after meals to reduce gastrointestinal irritation.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, pulmonological diagnosis, or respiratory management recommendations. Inhalation therapies and allergy medications should be used strictly under the guidance of a qualified pulmonologist or registered medical practitioner.
Acetylcysteine Tablets 600 mg
Acetylcysteine Tablets / Effervescent Tablets (600mg) is an oral mucolytic and intracellular antioxidant precursor on the WHO Model List of Essential Medicines. Its free sulfhydryl (-SH) group chemically splits disulfide bonds in mucoprotein complexes, breaking cross-linked polymers and dramatically reducing the viscosity of purulent, thick bronchial mucus to facilitate expectoration. It also replenishes intracellular cysteine pools for glutathione synthesis, protecting lung tissues against oxidative stress. Indicated for acute and chronic bronchopulmonary disorders with excessive, viscous mucus (COPD, chronic bronchitis, bronchiectasis, cystic fibrosis) and contrast-induced nephropathy prevention.
Acebrophylline Capsules 100 mg
Acebrophylline Capsules / Tablets (100mg, 200mg Sustained Release; alone or with Montelukast 10mg or Acetylcysteine 600mg) is a fixed salt of ambroxol and theophylline-7-acetic acid on the PMBI formulary. It exerts a triple therapeutic action: potent bronchodilation via phosphodiesterase inhibition; mucoregulatory and surfactant-stimulating action via ambroxol (stimulating alveolar type II pneumocytes to produce pulmonary surfactant, reducing mucus viscosity and improving mucociliary clearance); and anti-inflammatory inhibition of phospholipase A2 and leukotriene C4. Indicated for bronchial asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, and chronic spastic bronchitis with thick viscid sputum.
Acetylcysteine Injection 200 mg per ml
Acetylcysteine Injection (200mg/ml) is a sterile parenteral mucolytic and life-saving antidote on the WHO Model List of Essential Medicines. In paracetamol (acetaminophen) overdose, it replenishes depleted intracellular hepatic glutathione stores and conjugates directly with toxic NAPQI (N-acetyl-p-benzoquinone imine), preventing fatal hepatic centrilobular necrosis. Indicated as the specific antidote for acute paracetamol overdose and as an intravenous mucolytic in atelectasis / thick mucous plugging.
Acebrophylline 200mg (Sustained Release) + Montelukast 10mg Tablets
Acebrophylline Capsules / Tablets (100mg, 200mg Sustained Release; alone or with Montelukast 10mg or Acetylcysteine 600mg) is a fixed salt of ambroxol and theophylline-7-acetic acid on the PMBI formulary. It exerts a triple therapeutic action: potent bronchodilation via phosphodiesterase inhibition; mucoregulatory and surfactant-stimulating action via ambroxol (stimulating alveolar type II pneumocytes to produce pulmonary surfactant, reducing mucus viscosity and improving mucociliary clearance); and anti-inflammatory inhibition of phospholipase A2 and leukotriene C4. Indicated for bronchial asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, and chronic spastic bronchitis with thick viscid sputum.