TabletsClinical Overview
Telmisartan, Amlodipine, and Hydrochlorothiazide is a triple-action fixed-dose antihypertensive combination uniting three complementary hemodynamic mechanisms: an angiotensin II receptor blocker (ARB), a dihydropyridine calcium channel blocker (CCB), and a thiazide diuretic. Telmisartan blocks AT1 receptors and activates PPAR-gamma; amlodipine relaxes peripheral arterial smooth muscle; and hydrochlorothiazide promotes natriuresis, eliminating excess intravascular volume. Indicated for moderate-to-severe essential hypertension in patients not adequately controlled on dual-therapy regimens.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once daily in the morning with a glass of water, with or without food. Maintain regular morning administration to align with circadian blood pressure spikes. Never discontinue abruptly.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Peripheral ankle edema, dizziness, fatigue, headache, flushing, nausea, hypokalemia, hyperuricemia. Rare/Severe: Boxed warning: Fetal toxicity in pregnancy; severe hypotension/syncope, acute kidney injury, electrolyte imbalances, and angle-closure glaucoma.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black box warning: Discontinue immediately if pregnancy is detected; causes severe fetal injury and death. Contraindicated in anuria, severe hepatic impairment, and refractory hypokalemia. Regularly monitor serum electrolytes (potassium, sodium), BUN, and serum creatinine.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified cardiologist/pharmacist before initiating, altering, or substituting any cardiovascular medication.
Amlodipine 5mg + Atenolol 50mg Tablets
Amlodipine and Atenolol is a classic dual-mechanism cardiovascular combination pairing a dihydropyridine calcium channel blocker with a cardioselective beta-1 blocker. Amlodipine lowers peripheral vascular resistance and dilates coronary arteries, while atenolol reduces resting and exercise heart rates, suppresses cardiac contractility, and eliminates the reflex tachycardia typically triggered by dihydropyridine vasodilation. Indicated for essential hypertension and stable chronic angina pectoris.
Amlodipine Tablets 5mg
Amlodipine (or S-Amlodipine, the pure chirally active enantiomer with lower incidence of ankle edema) is a third-generation dihydropyridine calcium channel blocker on the WHO Model List of Essential Medicines. It inhibits transmembrane influx of extracellular calcium ions into vascular smooth muscle and cardiac muscle through L-type channels, resulting in potent peripheral arterial and coronary vasodilation with an exceptionally long half-life (30-50 hours). Indicated for essential hypertension, chronic stable angina pectoris, and vasospastic (Prinzmetal's) angina.
Amlodipine 5mg + Lisinopril 5mg Tablets
Amlodipine (or S-Amlodipine, the pure chirally active enantiomer with lower incidence of ankle edema) is a third-generation dihydropyridine calcium channel blocker on the WHO Model List of Essential Medicines. It inhibits transmembrane influx of extracellular calcium ions into vascular smooth muscle and cardiac muscle through L-type channels, resulting in potent peripheral arterial and coronary vasodilation with an exceptionally long half-life (30-50 hours). Indicated for essential hypertension, chronic stable angina pectoris, and vasospastic (Prinzmetal's) angina.
Losartan Potassium 50mg + Hydrochlorothiazide 12.5mg Tabelts
Losartan Potassium and Hydrochlorothiazide combines a selective AT1 receptor blocker with a thiazide diuretic on the WHO Model List of Essential Medicines. Losartan blocks angiotensin II-induced vasoconstriction and uniquely possesses intrinsic uricosuric properties that increase uric acid excretion, offsetting the hyperuricemic tendency of hydrochlorothiazide, while hydrochlorothiazide reduces extracellular fluid volume. Indicated for the treatment of hypertension not adequately controlled on monotherapy and for reducing stroke risk in hypertensive patients with left ventricular hypertrophy.