TabletsClinical Overview
Paracetamol / Acetaminophen (Tablets 500mg, 650mg, 1000mg; Oral Suspension 120mg, 125mg, 250mg per 5ml; Drops 100mg/ml) is a first-line non-opioid analgesic and antipyretic on the WHO Model List of Essential Medicines. It selectively inhibits central prostaglandin synthesis through peroxidase-dependent inhibition of COX enzymes in the brain and spinal cord, activates descending serotonergic inhibitory pathways, and resets the hypothalamic thermoregulatory center to reduce fever through cutaneous vasodilation and sweating. Unlike NSAIDs, it does NOT inhibit peripheral cyclooxygenase, causing zero gastric mucosal ulceration, platelet dysfunction, or renal vasoconstriction. Indicated as first-line therapy for mild-to-moderate pain (headache, toothache, dysmenorrhea, osteoarthritis) and fever of diverse etiologies.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Adults: Take 500 mg to 1000 mg orally every 4 to 6 hours as needed with water (maximum 4000 mg daily). Children: Dose strictly by weight: 10 to 15 mg/kg per dose every 4 to 6 hours (maximum 60 mg/kg/day or 4 doses in 24 hours). Measure pediatric suspensions/drops with a calibrated syringe or measuring cup. Can be taken with or without food.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Extremely well tolerated at therapeutic doses. Common: Rare mild nausea or rash. Rare/Severe: Acute dose-dependent hepatic necrosis (with doses >7.5-10 g in adults), acute liver failure, and severe cutaneous adverse reactions (Stevens-Johnson syndrome, TEN).
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Over-The-Counter analgesic/antipyretic. Do NOT exceed 4000 mg daily in adults (or 10-15 mg/kg/dose in children); accidental overdose causes fatal, irreversible acute liver failure. Avoid combining multiple OTC cough/cold medicines containing paracetamol. Chronic alcohol users (>3 drinks/day) should not exceed 2000 mg daily. N-acetylcysteine (NAC) is the specific antidote for acute toxicity.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or analgesic treatment guidance. Always consult a registered physician or orthopedic specialist before taking pain relievers, anti-inflammatory medications, or anti-arthritic therapies.
Aceclofenac 100mg + Paracetamol 325mg Tablets
Paracetamol / Acetaminophen (Tablets 500mg, 650mg, 1000mg; Oral Suspension 120mg, 125mg, 250mg per 5ml; Drops 100mg/ml) is a first-line non-opioid analgesic and antipyretic on the WHO Model List of Essential Medicines. It selectively inhibits central prostaglandin synthesis through peroxidase-dependent inhibition of COX enzymes in the brain and spinal cord, activates descending serotonergic inhibitory pathways, and resets the hypothalamic thermoregulatory center to reduce fever through cutaneous vasodilation and sweating. Unlike NSAIDs, it does NOT inhibit peripheral cyclooxygenase, causing zero gastric mucosal ulceration, platelet dysfunction, or renal vasoconstriction. Indicated as first-line therapy for mild-to-moderate pain (headache, toothache, dysmenorrhea, osteoarthritis) and fever of diverse etiologies.
Chlorzoxazone 500mg + Diclofenac 50mg + Paracetamol 325mg Tablets
Paracetamol (325mg/500mg) and Chlorzoxazone (250mg) Tablets is a centrally acting skeletal muscle relaxant and analgesic combination. Chlorzoxazone inhibits multi-synaptic reflex arcs in the spinal cord and subcortical areas of the brain, relieving painful skeletal muscle spasms. Paracetamol acts centrally to alleviate associated pain and discomfort. Indicated for acute, painful musculoskeletal conditions, muscle spasms, lumbago, torticollis, and strain/sprain trauma.
Ibuprofen Tablets 200 mg
Ibuprofen Tablets (200mg, 400mg) is an oral propionic acid derivative non-steroidal anti-inflammatory drug (NSAID) on the WHO Model List of Essential Medicines. It reversibly and non-selectively inhibits cyclooxygenase-1 and cyclooxygenase-2 enzymes, blocking synthesis of pro-inflammatory prostaglandins. Displays the most favorable gastrointestinal toxicity profile among non-selective NSAIDs at OTC analgesic doses (<=1200 mg/day). Indicated for mild-to-moderate pain (headache, dental pain, dysmenorrhea, backache), fever, osteoarthritis, and rheumatoid arthritis.
Ibuprofen Tablets 400 mg
Ibuprofen Tablets (200mg, 400mg) is an oral propionic acid derivative non-steroidal anti-inflammatory drug (NSAID) on the WHO Model List of Essential Medicines. It reversibly and non-selectively inhibits cyclooxygenase-1 and cyclooxygenase-2 enzymes, blocking synthesis of pro-inflammatory prostaglandins. Displays the most favorable gastrointestinal toxicity profile among non-selective NSAIDs at OTC analgesic doses (<=1200 mg/day). Indicated for mild-to-moderate pain (headache, dental pain, dysmenorrhea, backache), fever, osteoarthritis, and rheumatoid arthritis.