TabletsClinical Overview
Allylestrenol Tablets 5 mg is a synthetic oral progestogen derivative of 19-nortestosterone designed specifically for obstetric support. It stimulates placental trophoblast activity, enhances endogenous placental progesterone and human chorionic gonadotrophin (hCG) synthesis, normalizes oxytocinase levels, and suppresses myometrial hypercontractility without exerting androgenic or estrogenic virilizing effects on the female fetus. Indicated for threatened miscarriage, habitual abortion, threatened preterm labor, and intrauterine growth restriction (IUGR) due to placental insufficiency.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally with water, with or without food: For threatened abortion: 5 mg three times daily for 5 to 7 days until bleeding ceases, then gradually tapered. For habitual abortion: 5 to 10 mg daily starting as soon as pregnancy is confirmed and continued for at least one month past the critical period of previous miscarriages. For threatened preterm labor: dose titrated up to 10 mg three times daily as guided by obstetrician.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Mild gastrointestinal discomfort, nausea, headache, dizziness, and mild fluid retention. Rare/Severe: Liver enzyme elevations, hypersensitivity rash, and thromboembolic tendencies.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in undiagnosed abnormal vaginal bleeding, active thromboembolic disease, missed abortion, and severe hepatic dysfunction. Periodic ultrasound assessments to confirm fetal viability are recommended.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Gynecological, Obstetric & Endocrinological Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice or reproductive healthcare guidance. Hormonal medications, uterotonics, corticosteroids, fertility therapies, and emergency contraceptives have profound systemic actions and must be administered strictly under the supervision of a registered gynecologist, obstetrician, or endocrinologist.