Meropenem
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Antibiotics & Anti-Infectives treatment.
🧴 Clinical Application
Administered solely by healthcare professionals by intravenous bolus injection over 3-5 minutes or IV infusion over 15 to 30 minutes after reconstitution with sterile diluent. In severe hospital infections, prolonged infusions over 3 hours are used to maximize pharmacodynamic time above MIC.
⚠️ Side Effects
Common: Diarrhea, nausea, vomiting, headache, rash, thrombophlebitis at injection site, transient elevation of transaminases. Rare/Severe: Seizures and encephalopathy, anaphylactic shock, pseudomembranous colitis, and severe cutaneous adverse reactions.
🛡️ Safety Warnings
Contraindicated in carbapenem allergy. Absolute precaution: Concomitant administration with valproic acid causes rapid, profound drop in serum valproate concentrations, leading to loss of seizure control; combination should generally be avoided. Adjust dose in renal impairment.
Jan Aushadhi Products containing Meropenem
Found 3 generic formulation(s) containing this active ingredient.
Meropenem Injection 1 g
Meropenem is an intravenous synthetic carbapenem bactericidal antibiotic with broad-spectrum activity against Gram-positive, Gram-negative, and anaerobic pathogens. It acts by inhibiting bacterial cell wall synthesis via high-affinity binding to essential PBPs (PBP 2, 3, and 4). Has low epileptogenic potential compared to imipenem. Indicated for complicated intra-abdominal infections, complicated skin and soft tissue infections, bacterial meningitis in paediatric and adult patients, nosocomial pneumonia, and febrile neutropenia.
Meropenem 1000mg + Sulbactam 500mg Injection
Meropenem and Sulbactam is a potent ultra-broad-spectrum parenteral carbapenem-beta-lactamase inhibitor combination. Meropenem resists degradation by renal dehydropeptidase-1 and binds penicillin-binding proteins with high affinity, while sulbactam neutralizes beta-lactamases and exerts direct bactericidal activity against Acinetobacter baumannii. Indicated for life-threatening nosocomial infections, ventilator-associated pneumonia, septicemia, complicated intra-abdominal infections, and severe surgical sepsis caused by MDR pathogens.
Meropenem Injection 500 mg
Meropenem is an intravenous synthetic carbapenem bactericidal antibiotic with broad-spectrum activity against Gram-positive, Gram-negative, and anaerobic pathogens. It acts by inhibiting bacterial cell wall synthesis via high-affinity binding to essential PBPs (PBP 2, 3, and 4). Has low epileptogenic potential compared to imipenem. Indicated for complicated intra-abdominal infections, complicated skin and soft tissue infections, bacterial meningitis in paediatric and adult patients, nosocomial pneumonia, and febrile neutropenia.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Meropenem.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Meropenem Injection 1 g | Vial & Wfi | ₹221.25 | Mero | ₹876.90 | 75% Save |
| Meropenem 1000mg + Sulbactam 500mg Injection | Vial & Wfi | ₹268.13 | ALKEM LABORATORIES LTD, MEROPOL | ₹2045.17 | 87% Save |
| Meropenem Injection 500 mg | Vial & Wfi | ₹154.69 | TRUEPENAM, MERO, MEROMAC | ₹521.06 | 70% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Meropenem generics.