Gabapentin

Gabapentin is a structural GABA analogue that acts selectively by binding to the alpha-2-delta-1 subunit of presynaptic voltage-dependent calcium channels, attenuating calcium influx in hyper-excited spinal and cerebral neurons. Indicated for post-herpetic neuralgia, painful diabetic peripheral neuropathy, and adjunctive therapy in partial-onset seizures with or without secondary generalization.

Gabapentin is a structural GABA analogue that acts selectively by binding to the alpha-2-delta-1 subunit of presynaptic voltage-dependent calcium channels, attenuating calcium influx in hyper-excited spinal and cerebral neurons. Indicated for post-herpetic neuralgia, painful diabetic peripheral neuropathy, and adjunctive therapy in partial-onset seizures with or without secondary generalization.

Gabapentin and Nortriptyline is a dual-acting neuropathic pain formulation combining a gabapentinoid with a tricyclic antidepressant. Gabapentin decreases excitatory neurotransmitter exocytosis by binding to alpha-2-delta subunits of voltage-gated calcium channels, while nortriptyline blocks presynaptic reuptake of noradrenaline and serotonin, reinforcing endogenous descending spinal analgesia. Indicated for diabetic peripheral neuropathy, post-herpetic neuralgia, and chronic radiculopathy.

Gabapentin (300mg) and Amitriptyline (10mg) Tablets combines an alpha-2-delta calcium channel ligand with a tricyclic antidepressant. Gabapentin reduces excitatory neurotransmitter release, while amitriptyline potentiates descending serotonergic/noradrenergic inhibitory pain pathways. Indicated for chronic refractory neurogenic cough, post-herpetic neuralgia, and neuropathic pain syndromes.

Gabapentin is a structural GABA analogue that acts selectively by binding to the alpha-2-delta-1 subunit of presynaptic voltage-dependent calcium channels, attenuating calcium influx in hyper-excited spinal and cerebral neurons. Indicated for post-herpetic neuralgia, painful diabetic peripheral neuropathy, and adjunctive therapy in partial-onset seizures with or without secondary generalization.

Gabapentin is a structural GABA analogue that acts selectively by binding to the alpha-2-delta-1 subunit of presynaptic voltage-dependent calcium channels, attenuating calcium influx in hyper-excited spinal and cerebral neurons. Indicated for post-herpetic neuralgia, painful diabetic peripheral neuropathy, and adjunctive therapy in partial-onset seizures with or without secondary generalization.

Gabapentin is a structural GABA analogue that acts selectively by binding to the alpha-2-delta-1 subunit of presynaptic voltage-dependent calcium channels, attenuating calcium influx in hyper-excited spinal and cerebral neurons. Indicated for post-herpetic neuralgia, painful diabetic peripheral neuropathy, and adjunctive therapy in partial-onset seizures with or without secondary generalization.

Gabapentin and Nortriptyline is a dual-acting neuropathic pain formulation combining a gabapentinoid with a tricyclic antidepressant. Gabapentin decreases excitatory neurotransmitter exocytosis by binding to alpha-2-delta subunits of voltage-gated calcium channels, while nortriptyline blocks presynaptic reuptake of noradrenaline and serotonin, reinforcing endogenous descending spinal analgesia. Indicated for diabetic peripheral neuropathy, post-herpetic neuralgia, and chronic radiculopathy.

Gabapentin, Lignocaine (Lidocaine), and Baclofen topical gel is a localized multi-modal compound for refractory neuropathic and musculoskeletal pain. Gabapentin provides regional neuro-inhibition via calcium channel modulation; lignocaine reversibly blocks neuronal sodium channels to arrest pain impulse conduction; and baclofen activates GABAB receptors, inducing local skeletal muscle relaxation and mitigating spastic myofascial trigger points. Indicated for localized post-herpetic neuralgia, superficial neuropathic pain, and focal myofascial pain syndromes.