TabletsClinical Overview
Gabapentin and Nortriptyline is a dual-acting neuropathic pain formulation combining a gabapentinoid with a tricyclic antidepressant. Gabapentin decreases excitatory neurotransmitter exocytosis by binding to alpha-2-delta subunits of voltage-gated calcium channels, while nortriptyline blocks presynaptic reuptake of noradrenaline and serotonin, reinforcing endogenous descending spinal analgesia. Indicated for diabetic peripheral neuropathy, post-herpetic neuralgia, and chronic radiculopathy.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once daily at bedtime with water, with or without food. Bedtime administration helps alleviate daytime drowsiness and orthostasis. Avoid abrupt discontinuation.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Sedation, dry mouth, dizziness, constipation, weight gain, blurred vision. Rare/Severe: Cardiac conduction abnormalities, orthostatic hypotension, suicidal thoughts, and urinary retention.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in recent myocardial infarction, heart failure, and concurrent MAOIs. Caution in elderly patients, benign prostatic hyperplasia, and narrow-angle glaucoma. Avoid alcohol.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Nortriptyline Tablets 25mg
Nortriptyline Hydrochloride is a secondary amine tricyclic antidepressant and the active demethylated metabolite of amitriptyline. It selectively inhibits the reuptake of norepinephrine over serotonin, offering effective antidepressant and neuropathic analgesia with significantly less sedation, anticholinergic burden, and orthostatic hypotension than amitriptyline. Indicated for major depressive disorder and chronic neuropathic pain syndromes.
Gabapentin 100mg + Methylcobalamin 500mcg Tablets
Gabapentin is a structural GABA analogue that acts selectively by binding to the alpha-2-delta-1 subunit of presynaptic voltage-dependent calcium channels, attenuating calcium influx in hyper-excited spinal and cerebral neurons. Indicated for post-herpetic neuralgia, painful diabetic peripheral neuropathy, and adjunctive therapy in partial-onset seizures with or without secondary generalization.
Gabapentin Capsules 300mg
Gabapentin is a structural GABA analogue that acts selectively by binding to the alpha-2-delta-1 subunit of presynaptic voltage-dependent calcium channels, attenuating calcium influx in hyper-excited spinal and cerebral neurons. Indicated for post-herpetic neuralgia, painful diabetic peripheral neuropathy, and adjunctive therapy in partial-onset seizures with or without secondary generalization.
Gabapentin 400mg + Nortriptyline 10mg Tablets
Gabapentin and Nortriptyline is a dual-acting neuropathic pain formulation combining a gabapentinoid with a tricyclic antidepressant. Gabapentin decreases excitatory neurotransmitter exocytosis by binding to alpha-2-delta subunits of voltage-gated calcium channels, while nortriptyline blocks presynaptic reuptake of noradrenaline and serotonin, reinforcing endogenous descending spinal analgesia. Indicated for diabetic peripheral neuropathy, post-herpetic neuralgia, and chronic radiculopathy.