TabletsClinical Overview
Gabapentin is a structural GABA analogue that acts selectively by binding to the alpha-2-delta-1 subunit of presynaptic voltage-dependent calcium channels, attenuating calcium influx in hyper-excited spinal and cerebral neurons. Indicated for post-herpetic neuralgia, painful diabetic peripheral neuropathy, and adjunctive therapy in partial-onset seizures with or without secondary generalization.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally with a full glass of water, with or without meals. Space doses evenly throughout the day, ensuring the maximum interval between evening and morning doses does not exceed 12 hours. Do not discontinue abruptly; taper over at least one week.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Somnolence, dizziness, ataxia, fatigue, nystagmus, peripheral edema, viral infection in children. Rare/Severe: Serious respiratory depression (especially in combination with opioids or respiratory compromise), anaphylaxis/angioedema, DRESS syndrome, and suicidality.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
FDA warning on serious breathing difficulties in patients using opioids, other CNS depressants, or with underlying respiratory disease. Dose must be adjusted according to creatinine clearance in renal impairment. Antacids containing aluminum or magnesium reduce bioavailability; separate by at least 2 hours.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Gabapentin 100mg + Methylcobalamin 500mcg Tablets
Gabapentin is a structural GABA analogue that acts selectively by binding to the alpha-2-delta-1 subunit of presynaptic voltage-dependent calcium channels, attenuating calcium influx in hyper-excited spinal and cerebral neurons. Indicated for post-herpetic neuralgia, painful diabetic peripheral neuropathy, and adjunctive therapy in partial-onset seizures with or without secondary generalization.
Gabapentin Capsules 300mg
Gabapentin is a structural GABA analogue that acts selectively by binding to the alpha-2-delta-1 subunit of presynaptic voltage-dependent calcium channels, attenuating calcium influx in hyper-excited spinal and cerebral neurons. Indicated for post-herpetic neuralgia, painful diabetic peripheral neuropathy, and adjunctive therapy in partial-onset seizures with or without secondary generalization.
Gabapentin 400mg + Nortriptyline 10mg Tablets
Gabapentin and Nortriptyline is a dual-acting neuropathic pain formulation combining a gabapentinoid with a tricyclic antidepressant. Gabapentin decreases excitatory neurotransmitter exocytosis by binding to alpha-2-delta subunits of voltage-gated calcium channels, while nortriptyline blocks presynaptic reuptake of noradrenaline and serotonin, reinforcing endogenous descending spinal analgesia. Indicated for diabetic peripheral neuropathy, post-herpetic neuralgia, and chronic radiculopathy.
Gabapentin 300mg + Amitriptyline 10mg Tablets
Gabapentin (300mg) and Amitriptyline (10mg) Tablets combines an alpha-2-delta calcium channel ligand with a tricyclic antidepressant. Gabapentin reduces excitatory neurotransmitter release, while amitriptyline potentiates descending serotonergic/noradrenergic inhibitory pain pathways. Indicated for chronic refractory neurogenic cough, post-herpetic neuralgia, and neuropathic pain syndromes.