Duloxetine
Active pharmaceutical substance formulated in Jan Aushadhi generic products for CNS, Nerve & Mental Health treatment.
🧴 Clinical Application
Swallow whole with a full glass of water, with or without meals. Do not chew, crush, or open capsules to sprinkle pellets, as acid exposure inactivates the medication. Do not discontinue abruptly; taper gradually.
⚠️ Side Effects
Common: Nausea, dry mouth, somnolence, constipation, insomnia, dizziness, fatigue, diaphoresis. Rare/Severe: Boxed warning: Suicidal ideation; hepatotoxicity/hepatic failure, orthostatic hypotension, serotonin syndrome, and urinary retention.
🛡️ Safety Warnings
Boxed warning for suicidality in young adults. Contraindicated in patients with hepatic impairment, severe renal impairment (CrCl < 30 mL/min), or uncontrolled narrow-angle glaucoma. Monitor blood pressure and liver enzymes regularly. Avoid heavy alcohol use.
Jan Aushadhi Products containing Duloxetine
Found 5 generic formulation(s) containing this active ingredient.
Duloxetine Gastro-resistant Tablets 20 mg
Duloxetine is a potent, balanced dual serotonin and norepinephrine reuptake inhibitor (SNRI). It inhibits both 5-HT and NE reuptake in the central nervous system, boosting descending inhibitory pain pathways and elevating mood. Gastro-resistant formulation protects the acid-labile drug from gastric degradation. Indicated for major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain.
Duloxetine Gastro Resistant Tablets 30mg
Duloxetine is a potent, balanced dual serotonin and norepinephrine reuptake inhibitor (SNRI). It inhibits both 5-HT and NE reuptake in the central nervous system, boosting descending inhibitory pain pathways and elevating mood. Gastro-resistant formulation protects the acid-labile drug from gastric degradation. Indicated for major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain.
Pregabalin 75mg + Duloxetin (Delayed Release) 30mg Capsules
Pregabalin and Duloxetine is a synergistic dual-mechanism neuro-analgesic formulation. Pregabalin reduces presynaptic excitatory neurotransmitter release by modulating neuronal voltage-gated calcium channels, while duloxetine, a potent serotonin and noradrenaline reuptake inhibitor (SNRI), amplifies descending central monoaminergic inhibitory pain pathways. Indicated for refractory peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain.
Pregabalin 75mg + Duloxetin (Delayed Release) 20mg Capsules
Pregabalin and Duloxetine is a synergistic dual-mechanism neuro-analgesic formulation. Pregabalin reduces presynaptic excitatory neurotransmitter release by modulating neuronal voltage-gated calcium channels, while duloxetine, a potent serotonin and noradrenaline reuptake inhibitor (SNRI), amplifies descending central monoaminergic inhibitory pain pathways. Indicated for refractory peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain.
Pregabalin 50mg + Duloxetin (Delayed Release) 20mg Capsules
Pregabalin and Duloxetine is a synergistic dual-mechanism neuro-analgesic formulation. Pregabalin reduces presynaptic excitatory neurotransmitter release by modulating neuronal voltage-gated calcium channels, while duloxetine, a potent serotonin and noradrenaline reuptake inhibitor (SNRI), amplifies descending central monoaminergic inhibitory pain pathways. Indicated for refractory peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Duloxetine.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Duloxetine Gastro-resistant Tablets 20 mg | 10's | ₹27.84 | PREGABA, PREGABID | ₹202.09 | 86% Save |
| Duloxetine Gastro Resistant Tablets 30mg | 10's | ₹28.13 | TRETIVA, ASIDITAA | ₹220.74 | 87% Save |
| Pregabalin 75mg + Duloxetin (Delayed Release) 30mg Capsules | 10's | ₹51.56 | PREGEB | ₹306.65 | 83% Save |
| Pregabalin 75mg + Duloxetin (Delayed Release) 20mg Capsules | 10's | ₹42.19 | PREGABA, PREGABANYL, PREGABID | ₹217.95 | 81% Save |
| Pregabalin 50mg + Duloxetin (Delayed Release) 20mg Capsules | 10's | ₹32.81 | PREGABA, PREGABID, MAXDULIN | ₹142.64 | 77% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Duloxetine generics.