Dorzolamide
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Eye & Ear Care treatment.
🧴 Clinical Application
Instill one drop into the affected eye(s) once or twice daily. Apply gentle finger pressure to the inner corner of the eye (nasolacrimal occlusion) for 2 minutes immediately after instillation to minimize systemic cardiovascular and pulmonary absorption.
⚠️ Side Effects
Common: Transient eye burning, stinging, dry eyes, blurred vision. Rare/Severe: Systemic beta-blocker absorption: severe bradycardia, heart block, hypotension, syncope, bronchospasm, and exacerbation of congestive heart failure.
🛡️ Safety Warnings
Black box caution for systemic beta-blockade: Strictly contraindicated in bronchial asthma, severe COPD, sinus bradycardia, second- or third-degree AV block, and cardiogenic shock. Diabetic patients must be warned that timolol masks hypoglycemic tachycardia.
Jan Aushadhi Products containing Dorzolamide
Found 2 generic formulation(s) containing this active ingredient.
Dorzolamide 2% w/v + Timolol 0.5% w/v Eye Drops
Timolol Maleate (0.5% w/v) is a non-selective beta-1 and beta-2 adrenergic receptor antagonist on the WHO Model List of Essential Medicines. It blocks beta-adrenergic receptors on non-pigmented ciliary epithelial cells, inhibiting cyclic AMP synthesis and reducing aqueous humor secretion by 30-50% without altering pupillary size or accommodation. Indicated for lowering elevated intraocular pressure in patients with chronic open-angle glaucoma and ocular hypertension.
Dorzolamide Eye Drops 2% w/v
Topical Carbonic Anhydrase Inhibitor (Dorzolamide 2% or Brinzolamide 1% suspension, alone or with Timolol) on the WHO Model List of Essential Medicines. It inhibits carbonic anhydrase II (CA-II) in the ciliary processes, slowing bicarbonate ion formation and reducing active sodium and fluid transport, thereby diminishing aqueous humor secretion by up to 20-30%. Indicated for intraocular pressure reduction in open-angle glaucoma and ocular hypertension.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Dorzolamide.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Dorzolamide 2% w/v + Timolol 0.5% w/v Eye Drops | 5 ml | ₹150.00 | N/A | N/A | N/A |
| Dorzolamide Eye Drops 2% w/v | 5 ml | ₹103.13 | DORTAS | ₹467.26 | 78% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Dorzolamide generics.