Thyroid Hormone Regulators

Thyroxine Sodium (Levothyroxine, T4, 25 mcg - 150 mcg) is synthetic crystalline levothyroxine sodium on the WHO Model List of Essential Medicines. It is identical to endogenous T4 secreted by the human thyroid gland. In peripheral target tissues, it is deiodinated by iodothyronine deiodinases into active triiodothyronine (T3), which enters the cell nucleus to bind thyroid hormone receptors, regulating basal metabolic rate, protein synthesis, lipid and carbohydrate metabolism, and normal cardiovascular function. Narrow therapeutic index drug. Indicated for replacement therapy in primary, secondary, and tertiary hypothyroidism of any etiology, and pituitary TSH suppression in thyroid cancer.

Thyroxine Sodium (Levothyroxine, T4, 25 mcg - 150 mcg) is synthetic crystalline levothyroxine sodium on the WHO Model List of Essential Medicines. It is identical to endogenous T4 secreted by the human thyroid gland. In peripheral target tissues, it is deiodinated by iodothyronine deiodinases into active triiodothyronine (T3), which enters the cell nucleus to bind thyroid hormone receptors, regulating basal metabolic rate, protein synthesis, lipid and carbohydrate metabolism, and normal cardiovascular function. Narrow therapeutic index drug. Indicated for replacement therapy in primary, secondary, and tertiary hypothyroidism of any etiology, and pituitary TSH suppression in thyroid cancer.

Methimazole / Carbimazole (prodrug of methimazole) is a thionamide antithyroid drug on the WHO Model List of Essential Medicines. It inhibits the enzyme thyroid peroxidase (TPO), preventing the oxidation of iodide to iodine and blocking the organification and coupling of iodotyrosine residues on thyroglobulin, halting the synthesis of thyroid hormones T3 and T4. Indicated for the medical management of hyperthyroidism in Graves' disease, toxic multinodular goiter, preparation for radioactive iodine or thyroidectomy, and thyrotoxic crisis.

Methimazole / Carbimazole (prodrug of methimazole) is a thionamide antithyroid drug on the WHO Model List of Essential Medicines. It inhibits the enzyme thyroid peroxidase (TPO), preventing the oxidation of iodide to iodine and blocking the organification and coupling of iodotyrosine residues on thyroglobulin, halting the synthesis of thyroid hormones T3 and T4. Indicated for the medical management of hyperthyroidism in Graves' disease, toxic multinodular goiter, preparation for radioactive iodine or thyroidectomy, and thyrotoxic crisis.

Thyroxine Sodium (Levothyroxine, T4, 25 mcg - 150 mcg) is synthetic crystalline levothyroxine sodium on the WHO Model List of Essential Medicines. It is identical to endogenous T4 secreted by the human thyroid gland. In peripheral target tissues, it is deiodinated by iodothyronine deiodinases into active triiodothyronine (T3), which enters the cell nucleus to bind thyroid hormone receptors, regulating basal metabolic rate, protein synthesis, lipid and carbohydrate metabolism, and normal cardiovascular function. Narrow therapeutic index drug. Indicated for replacement therapy in primary, secondary, and tertiary hypothyroidism of any etiology, and pituitary TSH suppression in thyroid cancer.

Thyroxine Sodium (Levothyroxine, T4, 25 mcg - 150 mcg) is synthetic crystalline levothyroxine sodium on the WHO Model List of Essential Medicines. It is identical to endogenous T4 secreted by the human thyroid gland. In peripheral target tissues, it is deiodinated by iodothyronine deiodinases into active triiodothyronine (T3), which enters the cell nucleus to bind thyroid hormone receptors, regulating basal metabolic rate, protein synthesis, lipid and carbohydrate metabolism, and normal cardiovascular function. Narrow therapeutic index drug. Indicated for replacement therapy in primary, secondary, and tertiary hypothyroidism of any etiology, and pituitary TSH suppression in thyroid cancer.

Thyroxine Sodium (Levothyroxine, T4, 25 mcg - 150 mcg) is synthetic crystalline levothyroxine sodium on the WHO Model List of Essential Medicines. It is identical to endogenous T4 secreted by the human thyroid gland. In peripheral target tissues, it is deiodinated by iodothyronine deiodinases into active triiodothyronine (T3), which enters the cell nucleus to bind thyroid hormone receptors, regulating basal metabolic rate, protein synthesis, lipid and carbohydrate metabolism, and normal cardiovascular function. Narrow therapeutic index drug. Indicated for replacement therapy in primary, secondary, and tertiary hypothyroidism of any etiology, and pituitary TSH suppression in thyroid cancer.

Thyroxine Sodium (Levothyroxine, T4, 25 mcg - 150 mcg) is synthetic crystalline levothyroxine sodium on the WHO Model List of Essential Medicines. It is identical to endogenous T4 secreted by the human thyroid gland. In peripheral target tissues, it is deiodinated by iodothyronine deiodinases into active triiodothyronine (T3), which enters the cell nucleus to bind thyroid hormone receptors, regulating basal metabolic rate, protein synthesis, lipid and carbohydrate metabolism, and normal cardiovascular function. Narrow therapeutic index drug. Indicated for replacement therapy in primary, secondary, and tertiary hypothyroidism of any etiology, and pituitary TSH suppression in thyroid cancer.

Thyroxine Sodium (Levothyroxine, T4, 25 mcg - 150 mcg) is synthetic crystalline levothyroxine sodium on the WHO Model List of Essential Medicines. It is identical to endogenous T4 secreted by the human thyroid gland. In peripheral target tissues, it is deiodinated by iodothyronine deiodinases into active triiodothyronine (T3), which enters the cell nucleus to bind thyroid hormone receptors, regulating basal metabolic rate, protein synthesis, lipid and carbohydrate metabolism, and normal cardiovascular function. Narrow therapeutic index drug. Indicated for replacement therapy in primary, secondary, and tertiary hypothyroidism of any etiology, and pituitary TSH suppression in thyroid cancer.

Methimazole / Carbimazole (prodrug of methimazole) is a thionamide antithyroid drug on the WHO Model List of Essential Medicines. It inhibits the enzyme thyroid peroxidase (TPO), preventing the oxidation of iodide to iodine and blocking the organification and coupling of iodotyrosine residues on thyroglobulin, halting the synthesis of thyroid hormones T3 and T4. Indicated for the medical management of hyperthyroidism in Graves' disease, toxic multinodular goiter, preparation for radioactive iodine or thyroidectomy, and thyrotoxic crisis.

Methimazole / Carbimazole (prodrug of methimazole) is a thionamide antithyroid drug on the WHO Model List of Essential Medicines. It inhibits the enzyme thyroid peroxidase (TPO), preventing the oxidation of iodide to iodine and blocking the organification and coupling of iodotyrosine residues on thyroglobulin, halting the synthesis of thyroid hormones T3 and T4. Indicated for the medical management of hyperthyroidism in Graves' disease, toxic multinodular goiter, preparation for radioactive iodine or thyroidectomy, and thyrotoxic crisis.

Thyroxine Sodium (Levothyroxine, T4, 25 mcg - 150 mcg) is synthetic crystalline levothyroxine sodium on the WHO Model List of Essential Medicines. It is identical to endogenous T4 secreted by the human thyroid gland. In peripheral target tissues, it is deiodinated by iodothyronine deiodinases into active triiodothyronine (T3), which enters the cell nucleus to bind thyroid hormone receptors, regulating basal metabolic rate, protein synthesis, lipid and carbohydrate metabolism, and normal cardiovascular function. Narrow therapeutic index drug. Indicated for replacement therapy in primary, secondary, and tertiary hypothyroidism of any etiology, and pituitary TSH suppression in thyroid cancer.

Thyroxine Sodium (Levothyroxine, T4, 25 mcg - 150 mcg) is synthetic crystalline levothyroxine sodium on the WHO Model List of Essential Medicines. It is identical to endogenous T4 secreted by the human thyroid gland. In peripheral target tissues, it is deiodinated by iodothyronine deiodinases into active triiodothyronine (T3), which enters the cell nucleus to bind thyroid hormone receptors, regulating basal metabolic rate, protein synthesis, lipid and carbohydrate metabolism, and normal cardiovascular function. Narrow therapeutic index drug. Indicated for replacement therapy in primary, secondary, and tertiary hypothyroidism of any etiology, and pituitary TSH suppression in thyroid cancer.