CapsulesClinical Overview
Dehydroepiandrosterone (Micronized) 25 mg Capsule is an endogenous steroid prohormone synthesized by the adrenal cortex and ovarian theca cells. As a metabolic precursor to androstenedione, testosterone, and estrone, it plays a critical role in follicular steroidogenesis, enhancing preantral and antral follicle sensitivity to FSH via IGF-1 mediation. Indicated as an adjuvant reproductive therapy for diminished ovarian reserve (DOR), poor ovarian response (POR) in IVF cycles, advanced maternal reproductive age, and age-related hormonal insufficiency.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally 25 mg two to three times daily (total 50 to 75 mg daily) with meals and water, continuously for at least 8 to 16 weeks prior to planned ovarian stimulation / IVF cycle (matching the time window of follicular recruitment). Administer with food to optimize bioavailability.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Mild androgenic effects including acne, oily skin, increased facial hair growth (hirsutism), transient hair loss, insomnia, and mood fluctuations. Rare/Severe: Liver enzyme elevations, virilization with long-term high doses, and exacerbation of hormone-sensitive malignancies.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in hormone-sensitive breast, uterine, ovarian, or prostate cancers, and during pregnancy or lactation. Periodic monitoring of liver function tests and serum DHEA-S levels recommended. Discontinue once pregnancy is confirmed.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Gynecological, Obstetric & Endocrinological Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice or reproductive healthcare guidance. Hormonal medications, uterotonics, corticosteroids, fertility therapies, and emergency contraceptives have profound systemic actions and must be administered strictly under the supervision of a registered gynecologist, obstetrician, or endocrinologist.